Yuefeng Qi, Cui Jia, Lei Liu, Jin Zhang, Yanyan Liu, Wei Wang. Biosensing Properties of Nanofilm-Modified Long-Period Fiber Gratings[J]. Acta Optica Sinica, 2018, 38(10): 1006005
- Acta Optica Sinica
- Vol. 38, Issue 10, 1006005 (2018)
Fig. 1. Effects of the changes in the refractive index of the grating surface on the LPFG resonance peak
Fig. 2. Antigen-antibody reaction curve
Fig. 3. Schematic of the nanofilm-modified LPFG biosensor
Fig. 4. Fabrication of the sensitive film. (a) Surface modified with sulfuric acid; (b) surface modified with APTES; (c) surface modified with glutaric dialdehyde; (d) immobilization of the identifying biomolecules
Fig. 5. Microscopic images. (a) Grating area before the experiment; (b) nanofilm-modified LPFG biosensing area after the immunoassay
Fig. 6. Effects of the pre-chemical treatments on the resonance peak of LPFG
Fig. 7. Effects of the immunoassay on the resonance peak of LPFG at Λ=445 μm. (a) Concentration of rabbit IgG with 0.0025-0.0075 mg·mL-1; (b) concentration of rabbit IgG with 0.0075-0.0300 mg·mL-1
Fig. 8. Peak loss of LPFG at Λ=445 μm with different rabbit IgG concentrations
Fig. 9. Peak loss of LPFG with different rabbit IgG concentrations. (a) Λ = 460 μm; (b) Λ = 500 μm
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Table 1. Rabbit IgG concentrations corresponding to different period gratings
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