Virtual reality (VR) and its derivatives, namely augmented reality (AR) and mixed reality (MR), can overlap the three-dimensional virtual scene with the real world and can significantly improve the intuition, accuracy, and real-time nature of the user's sensory world. The popularization and application of this technology is expected to revolutionize the medical field. Herein, the concept of VR/AR/MR is analyzed and its development process is briefly described. The applications of VR and AR in the medical field are elaborated, and the advantages of solutions based on MR are analyzed based on HoloLens. Finally, the deficiencies of VR/AR/MR applications in the medical field are summarized, and the future development trend is prospected.