Reverse dispersion fiber (RDF) with depressed-core index profile is fabricated successfully by using plasma-activated chemical vapor phase deposition. The fabricated RDF has a core-effective-area of 45 μm2, dispersion of -19.65 ps/(nm?km) and dispersion slope of -0.132 ps/(nm2?km) while maintaining the low bending induced attenuation and low PMD value. Furthermore, the hydrogen induced attenuation at 1530 nm decreases to the value of less than 0.01 dB/km by optimizing the dopant concentration of different core layer. The dispersion managed pairs, consisting of RDF and non-zero dispersion shifted fiber with ultra large effective-core-area (ULAF), have the ultra low dispersion slope of less than 0.006 ps/(nm2·km) at the wavelength range from 1530 nm to 1625 nm, and the largest dispersion value is lower than 0.2 ps/(nm?km). Moreover, the attenuation characteristic also shows a remarkable flatness over the broad-band wavelength, and the attenuation at 1550 nm is as low as 0.224 dB/km. The dispersion managed pairs are applicable for large capacity, high bit-rate long-haul wavelength division multiplexing (WDM) transmission system without using dispersion compensation mode.