• Chinese Journal of Lasers
  • Vol. 49, Issue 5, 0507101 (2022)
Buhong Li1、*, Tianlong Chen1, Li Lin1, Bing Chen2, Haixia Qiu3, and Ying Gu3
Author Affiliations
  • 1MOE Key Laboratory of Optoelectronic Science and Technology for Medicine, Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fuzhou, Fujian 350117, China
  • 2Fuzhou Tucsen Photonics Co., Ltd., Fuzhou, Fujian 350007, China
  • 3Department of Laser Medicine, First Medical Center, Chinese PLA General Hospital, Beijing 100039, China
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    DOI: 10.3788/CJL202249.0507101 Cite this Article Set citation alerts
    Buhong Li, Tianlong Chen, Li Lin, Bing Chen, Haixia Qiu, Ying Gu. Recent Progress in Photodynamic Therapy: From Fundamental Research to Clinical Applications[J]. Chinese Journal of Lasers, 2022, 49(5): 0507101 Copy Citation Text show less
    References

    [1] Li B H, Lin L S, Lin H Y et al. Photosensitized singlet oxygen generation and detection: recent advances and future perspectives in cancer photodynamic therapy[J]. Journal of Biophotonics, 9, 1314-1325(2016).

    [2] Okunaka T, Usuda J, Ichinose S et al. A possible relationship between the anti-cancer potency of photodynamic therapy using the novel photosensitizer ATX-s10-Na(Ⅱ) and expression of the vascular endothelial growth factor in vivo[J]. Oncology Reports, 18, 679-683(2007).

    [3] Chen J J, Hou L J, Zheng K et al. Blood distribution and plasma protein binding of PHOTOCYANINE: a promising phthalocyanine photosensitizer inphase Ⅱ clinical trials[J]. European Journal of Pharmaceutical Sciences, 153, 105491(2020).

    [4] Lin L, Song X J, Dong X C et al. Nano-photosensitizers for enhanced photodynamic therapy[J]. Photodiagnosis and Photodynamic Therapy, 36, 102597(2021).

    [5] Pham T C, Nguyen V N, Choi Y et al. Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy[J]. Chemical Reviews, 121, 13454-13619(2021).

    [6] Liu X, Li R, Zhou Y et al. An all-in-one nanoplatform with near-infrared light promoted on-demand oxygen release and deep intratumoral penetration for synergistic photothermal/photodynamic therapy[J]. Journal of Colloid and Interface Science, 608, 1543-1552(2022).

    [7] Ge J C, Lan M H, Zhou B J et al. A graphene quantum dot photodynamic therapy agent with high singlet oxygen generation[J]. Nature Communications, 5, 4596(2014).

    [8] Kenry , Tang B Z, Liu B. Catalyst: aggregation-induced emission: how far have we come, and where are we going next?[J]. Chem, 6, 1195-1198(2020).

    [9] Xu W J, Qian J M, Hou G H et al. A dual-targeted hyaluronic acid-gold nanorod platform with triple-stimuli responsiveness for photodynamic/photothermal therapy of breast cancer[J]. Acta Biomaterialia, 83, 400-413(2019).

    [10] Wang P, Shi Y H, Zhang S C et al. Hydrogen peroxide responsive iron-based nanoplatform for multimodal imaging-guided cancer therapy[J]. Small, 15, e1803791(2019).

    [11] Alzeibak R, Mishchenko T A, Shilyagina N Y et al. Targeting immunogenic cancer cell death by photodynamic therapy: past, present and future[J]. Journal for Immunotherapy of Cancer, 9, e001926(2021).

    [12] Zhang X, Hou Y Q, Xiao X et al. Recent development of the transition metal complexes showing strong absorption of visible light and long-lived triplet excited state: from molecular structure design to photophysical properties and applications[J]. Coordination Chemistry Reviews, 417, 213371(2020).

    [13] Ryan R T, Stevens K C, Calabro R et al. Bis-tridentate N-heterocyclic carbene Ru(Ⅱ) complexes are promising new agents for photodynamic therapy[J]. Inorganic Chemistry, 59, 8882-8892(2020).

    [14] Tang Q Y, Cheng Z J, Yang N et al. Hydrangea-structured tumor microenvironment responsive degradable nanoplatform for hypoxic tumor multimodal imaging and therapy[J]. Biomaterials, 205, 1-10(2019).

    [15] Yang X, Yang Y, Gao F et al. Biomimetic hybrid nanozymes with self-supplied H+ and accelerated O2 generation for enhanced starvation and photodynamic therapy against hypoxic tumors[J]. Nano Letters, 19, 4334-4342(2019).

    [16] Yu Z Z, Zhou P, Pan W et al. A biomimetic nanoreactor for synergistic chemiexcited photodynamic therapy and starvation therapy against tumor metastasis[J]. Nature Communications, 9, 5044(2018).

    [17] Xu S T, Zhu X Y, Zhang C et al. Oxygen and Pt(Ⅱ) self-generating conjugate for synergistic photo-chemo therapy of hypoxic tumor[J]. Nature Communications, 9, 2053(2018).

    [18] Zhao X Z, Liu J P, Fan J L et al. Recent progress in photosensitizers for overcoming the challenges of photodynamic therapy: from molecular design to application[J]. Chemical Society Reviews, 50, 4185-4219(2021).

    [19] Lin L, Li B H. Application progress of light-emitting diode for photodynamic therapy[J]. Laser & Optoelectronics Progress, 57, 150001(2020).

    [20] Xiang M H, Zhou Q M, Shi Z H et al. A review of light sources and enhanced targeting for photodynamic therapy[J]. Current Medicinal Chemistry, 28, 6437-6457(2021).

    [21] Xu X Q, An H J, Zhang D L et al. A self-illuminating nanoparticle for inflammation imaging and cancer therapy[J]. Science Advances, 5, eaat2953(2019).

    [22] Kotagiri N, Laforest R, Achilefu S. Reply to ‘Is Cherenkov luminescence bright enough for photodynamic therapy? ’[J]. Nature Nanotechnology, 13, 354-355(2018).

    [23] Kim A, Zhou J W, Samaddar S et al. An implantable ultrasonically-powered micro-light-source (μLight) for photodynamic therapy[J]. Scientific Reports, 9, 1395(2019).

    [24] Wang G D, Nguyen H T, Chen H M et al. X-ray induced photodynamic therapy: a combination of radiotherapy and photodynamic therapy[J]. Theranostics, 6, 2295-2305(2016).

    [25] Kawamura K, Hikosou D, Inui A et al. Ultrasonic activation of water-soluble Au25(SR)18 nanoclusters for singlet oxygen production[J]. The Journal of Physical Chemistry C, 123, 26644-26652(2019).

    [26] Kamkaew A, Cheng L, Goel S et al. Cerenkov radiation induced photodynamic therapy using chlorin e6-loaded hollow mesoporous silica nanoparticles[J]. ACS Applied Materials & Interfaces, 8, 26630-26637(2016).

    [27] Kim S, Jo H, Jeon M et al. Luciferase-Rose Bengal conjugates for singlet oxygen generation by bioluminescence resonance energy transfer[J]. Chemical Communications, 53, 4569-4572(2017).

    [28] Kamanli A F, Çetinel G. Radiation mode and tissue thickness impact on singlet oxygen dosimetry methods for antimicrobial photodynamic therapy[J]. Photodiagnosis and Photodynamic Therapy, 36, 102483(2021).

    [29] Wei F M, Rees T W, Liao X X et al. Oxygen self-sufficient photodynamic therapy[J]. Coordination Chemistry Reviews, 432, 213714(2021).

    [30] Cheng Y H, Cheng H, Jiang C X et al. Perfluorocarbon nanoparticles enhance reactive oxygen levels and tumour growth inhibition in photodynamic therapy[J]. Nature Communications, 6, 8785(2015).

    [31] Wang P Y, Li X M, Yao C et al. Orthogonal near-infrared upconversion co-regulated site-specific O2 delivery and photodynamic therapy for hypoxia tumor by using red blood cell microcarriers[J]. Biomaterials, 125, 90-100(2017).

    [32] Yuan P, Ruan Z, Jiang W et al. Oxygen self-sufficient fluorinated polypeptide nanoparticles for NIR imaging-guided enhanced photodynamic therapy[J]. Journal of Materials Chemistry B, 6, 2323-2331(2018).

    [33] Gao S T, Zheng P L, Li Z H et al. Biomimetic O2-evolving metal-organic framework nanoplatform for highly efficient photodynamic therapy against hypoxic tumor[J]. Biomaterials, 178, 83-94(2018).

    [34] Zhu W W, Dong Z L, Fu T T et al. Modulation of hypoxia in solid tumor microenvironment with MnO2 nanoparticles to enhance photodynamic therapy[J]. Advanced Functional Materials, 26, 5490-5498(2016).

    [35] Huang C C, Chia W T, Chung M F et al. An implantable depot that can generate oxygen in situ for overcoming hypoxia-induced resistance to anticancer drugs in chemotherapy[J]. Journal of the American Chemical Society, 138, 5222-5225(2016).

    [36] Chen H C, Tian J W, He W J et al. H2O2-activatable and O2-evolving nanoparticles for highly efficient and selective photodynamic therapy against hypoxic tumor cells[J]. Journal of the American Chemical Society, 137, 1539-1547(2015).

    [37] Huo M F, Wang L Y, Zhang L L et al. Photosynthetic tumor oxygenation by photosensitizer-containing cyanobacteria for enhanced photodynamic therapy[J]. Angewandte Chemie, 59, 1906-1913(2020).

    [38] Ji Y, Lu F, Hu W B et al. Tandem activated photodynamic and chemotherapy: using pH-sensitive nanosystems to realize different tumour distributions of photosensitizer/prodrug for amplified combination therapy[J]. Biomaterials, 219, 119393(2019).

    [39] Cui D, Huang J G, Zhen X et al. A semiconducting polymer nano-prodrug for hypoxia-activated photodynamic cancer therapy[J]. Angewandte Chemie, 58, 5920-5924(2019).

    [40] Xia D L, Xu P P, Luo X Y et al. Overcoming hypoxia by multistage nanoparticle delivery system to inhibit mitochondrial respiration for photodynamic therapy[J]. Advanced Functional Materials, 29, 1807294(2019).

    [41] Chen D P, Yu Q, Huang X et al. A highly-efficient type Ⅰ photosensitizer with robust vascular-disruption activity for hypoxic-and-metastatic tumor specific photodynamic therapy[J]. Small, 16, e2001059(2020).

    [42] Bolze F, Jenni S, Sour A et al. Molecular photosensitisers for two-photon photodynamic therapy[J]. Chemical Communications, 53, 12857-12877(2017).

    [43] Zhu J W, Jiao A H, Li Q Z et al. Mitochondrial Ca2+-overloading by oxygen/glutathione depletion-boosted photodynamic therapy based on a CaCO3 nanoplatform for tumor synergistic therapy[J]. Acta Biomaterialia, 137, 252-261(2022).

    [44] Liu C H, Cao Y, Cheng Y R et al. An open source and reduce expenditure ROS generation strategy for chemodynamic/photodynamic synergistic therapy[J]. Nature Communications, 11, 1735(2020).

    [45] Yano T, Muto M, Minashi K et al. Long-term results of salvage photodynamic therapy for patients with local failure after chemoradiotherapy for esophageal squamous cell carcinoma[J]. Endoscopy, 43, 657-663(2011).

    [46] Yang J X, Hou M F, Sun W S et al. Sequential PDT and PTT using dual-modal single-walled carbon nanohorns synergistically promote systemic immune responses against tumor metastasis and relapse[J]. Advanced Science, 7, 2001088(2020).

    [47] Ma S H, Xie J, Wang L et al. Hetero-core-shell BiNS-Fe@Fe as a potential theranostic nanoplatform for multimodal imaging-guided simultaneous photothermal-photodynamic and chemodynamic treatment[J]. ACS Applied Materials & Interfaces, 13, 10728-10740(2021).

    [48] He C B, Duan X P, Guo N N et al. Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy[J]. Nature Communications, 7, 12499(2016).

    [49] Liu T T, Song Y, Huang Z B et al. Photothermal photodynamic therapy and enhanced radiotherapy of targeting copolymer-coated liquid metal nanoparticles on liver cancer[J]. Colloids and Surfaces B, 207, 112023(2021).

    [50] Wo F J, Xu R J, Shao Y X et al. A multimodal system with synergistic effects of magneto-mechanical, photothermal, photodynamic and chemo therapies of cancer in graphene-quantum dot-coated hollow magnetic nanospheres[J]. Theranostics, 6, 485-500(2016).

    [51] Qiu Z H, Yao G P, Chen D F et al. Determination of optical and microvascular parameters of port wine stains using diffuse reflectance spectroscopy[J]. Advances in Experimental Medicine and Biology, 923, 359-365(2016).

    [52] Teng X, Li F, Lu C et al. Carbon dot-assisted luminescence of singlet oxygen: the generation dynamics but not the cumulative amount of singlet oxygen is responsible for the photodynamic therapy efficacy[J]. Nanoscale Horizons, 5, 978-985(2020).

    [53] Li W B, Shen Y, Li B H. Advances in optical imaging for monitoring photodynamic therapy dosimetry[J]. Chinese Journal of Lasers, 47, 0207006(2020).

    [54] Xu X L, Lin L S, Li B H. Automatic protocol for quantifying the vasoconstriction in blood vessel images[J]. Biomedical Optics Express, 11, 2122-2136(2020).

    [55] Wilson B C, Patterson M S, Lilge L. Implicit and explicit dosimetry in photodynamic therapy: a new paradigm[J]. Lasers in Medical Science, 12, 182-199(1997).

    [56] Lin L S, Lin H Y, Shen Y et al. Singlet oxygen luminescence image in blood vessels during vascular-targeted photodynamic therapy[J]. Photochemistry and Photobiology, 96, 646-651(2020).

    [57] Moritz T J, Zhao Y B, Hinds M F et al. Multispectral singlet oxygen and photosensitizer luminescence dosimeter for continuous photodynamic therapy dose assessment during treatment[J]. Journal of Biomedical Optics, 25, 063810(2020).

    [58] Pogue B W, Elliott J T, Kanick S C et al. Revisiting photodynamic therapy dosimetry: reductionist & surrogate approaches to facilitate clinical success[J]. Physics in Medicine and Biology, 61, R57-R89(2016).

    [59] Hackbarth S, Islam W, Fang J et al. Singlet oxygen phosphorescence detection in vivo identifies PDT-induced anoxia in solid tumors[J]. Photochemical & Photobiological Sciences, 18, 1304-1314(2019).

    [60] Morozov P, Lukina M, Shirmanova M et al. Singlet oxygen phosphorescence imaging by superconducting single-photon detector and time-correlated single-photon counting[J]. Optics Letters, 46, 1217-1220(2021).

    [61] Zhao Y B, Moritz T, Hinds M F et al. High optical-throughput spectroscopic singlet oxygen and photosensitizer luminescence dosimeter for monitoring of photodynamic therapy[J]. Journal of Biophotonics, 14, e202100088(2021).

    [62] Betrouni N, Boukris S, Benzaghou F. Vascular targeted photodynamic therapy with TOOKAD® Soluble (WST11) in localized prostate cancer: efficiency of automatic pre-treatment planning[J]. Lasers in Medical Science, 32, 1301-1307(2017).

    [63] Ahn P H, Finlay J C, Gallagher-Colombo S M et al. Lesion oxygenation associates with clinical outcomes in premalignant and early stage head and neck tumors treated on a phase 1 trial of photodynamic therapy[J]. Photodiagnosis and Photodynamic Therapy, 21, 28-35(2018).

    [64] Ong Y H, Kim M M, Finlay J C et al. PDT dose dosimetry for Photofrin-mediated pleural photodynamic therapy (pPDT)[J]. Physics in Medicine and Biology, 63, 015031(2017).

    [65] Kim M M, Zhu T C, Ong Y H et al. Infrared navigation system for light dosimetry during pleural photodynamic therapy[J]. Physics in Medicine and Biology, 65, 075006(2020).

    [66] Ong Y H, Kim M M, Dimofte A et al. Reactive oxygen species explicit dosimetry for Photofrin-mediated pleural photodynamic therapy[J]. Photochemistry and Photobiology., 96, 340-348(2020).

    [67] Li X S, Lovell J F, Yoon J et al. Clinical development and potential of photothermal and photodynamic therapies for cancer[J]. Nature Reviews Clinical Oncology, 17, 657-674(2020).

    [68] Shen Y, Liang F Q, Niu Y H et al. Monitoring vascular targeted PDT response with multimode optical imaging[J]. Proceedings of SPIE, 10879, 1087906(2019).

    [69] Dolmans D E J G J, Fukumura D, Jain R K. Photodynamic therapy for cancer[J]. Nature Reviews Cancer, 3, 380-387(2003).

    [70] Li G, Wang Q, Liu J X et al. Innovative strategies for enhanced tumor photodynamic therapy[J]. Journal of Materials Chemistry B, 9, 7347-7370(2021).

    [71] Li L, Liu L, Wang Y et al. Simulation of spatial and temporal distribution of singlet oxygen in port wine stain during vascular targeted photodynamic therapy[J]. Proceedings of SPIE, 11190, 111902D(2019).

    [72] Xu X L, Shen Y, Lin L et al. Multi-step deep neural network for identifying subfascial vessels in a dorsal skinfold window chamber model[J]. Biomedical Optics Express, 13, 426-437(2021).

    [73] Cieplik F, Deng D M, Crielaard W et al. Antimicrobial photodynamic therapy: what we know and what we don’t[J]. Critical Reviews in Microbiology, 44, 571-589(2018).

    [74] Gilaberte Y, Rezusta A, Juarranz A et al. Editorial: antimicrobial photodynamic therapy: a new paradigm in the fight against infections[J]. Frontiers in Medicine, 8, 788888(2021).

    [75] Qiu H X, Mao Y P, Gu Y et al. The potential of photodynamic therapy to treat esophageal candidiasis coexisting with esophageal cancer[J]. Journal of Photochemistry and Photobiology B, 130, 305-309(2014).

    [76] Zeng B S, Zeng B Y, Hung C M et al. Efficacy and acceptability of different anti-fungal interventions in oropharyngeal or esophageal candidiasis in HIV co-infected adults: a pilot network meta-analysis[J]. Expert Review of Anti-Infective Therapy, 19, 1469-1479(2021).

    Buhong Li, Tianlong Chen, Li Lin, Bing Chen, Haixia Qiu, Ying Gu. Recent Progress in Photodynamic Therapy: From Fundamental Research to Clinical Applications[J]. Chinese Journal of Lasers, 2022, 49(5): 0507101
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