[1] J. Li, B. E.-F. de Ávila, W. Gao, L. Zhang, J. Wang. Micro/nanorobots for biomedicine: delivery, surgery, sensing, and detoxification. Sci. Robot., 2, eaam6431(2017).
[2] B. E.-F. de Ávila, P. Angsantikul, J. Li, M. Angel Lopez-Ramirez, D. E. Ramírez-Herrera, S. Thamphiwatana, C. Chen, J. Delezuk, R. Samakapiruk, V. Ramez, L. Zhang, J. Wang. Micromotor-enabled active drug delivery for in vivo treatment of stomach infection. Nat. Commun., 8, 272(2017).
[3] J. Li, X. Li, T. Luo, R. Wang, C. Liu, S. Chen, D. Li, J. Yue, S. H. Cheng, D. Sun. Development of a magnetic microrobot for carrying and delivering targeted cells. Sci. Robot., 3, eaat8829(2018).
[4] X. Z. Chen, B. Jang, D. Ahmed, C. Hu, C. De Marco, M. Hoop, F. Mushtaq, B. J. Nelson, S. Pané. Small-scale machines driven by external power sources. Adv. Mater., 30, 1705061(2018).
[5] Y. Wu, T. Si, J. Shao, Z. Wu, Q. He. Near-infrared light-driven Janus capsule motors: fabrication, propulsion, and simulation. Nano Res., 9, 3747(2016).
[6] H. Zeng, P. Wasylczyk, C. Parmeggiani, D. Martella, M. Burresi, D. S. Wiersma. Light-fueled microscopic walkers. Adv. Mater., 27, 3883(2015).
[7] S. Tottori, L. Zhang, F. Qiu, K. K. Krawczyk, A. Franco-Obregón, B. J. Nelson. Magnetic helical micromachines: fabrication, controlled swimming, and cargo transport. Adv. Mater., 24, 811(2012).
[8] C. Peters, M. Hoop, S. Pané, B. J. Nelson, C. Hierold. Degradable magnetic composites for minimally invasive interventions: device fabrication, targeted drug delivery, and cytotoxicity tests. Adv. Mater., 28, 533(2016).
[9] W. Gao, R. Dong, S. Thamphiwatana, J. Li, W. Gao, L. Zhang, J. Wang. Artificial micromotors in the mouse’s stomach: a step toward in vivo use of synthetic motors. ACS Nano., 9, 117(2015).
[10] D. Li, Y. Liu, Y. Yang, Y. Shen. A fast and powerful swimming microrobot with a serrated tail enhanced propulsion interface. Nanoscale, 10, 19673(2018).
[11] V. Magdanz, S. Sanchez, O. G. Schmidt. Development of a sperm-flagella driven micro-bio-robot. Adv. Mater., 25, 6581(2013).
[12] B. Esteban-Fernández de Ávila, P. Angsantikul, J. Li, W. Gao, L. Zhang, J. Wang. Micromotors go in vivo: from test tubes to live animals. Adv. Funct. Mater., 28, 1705640(2018).
[13] X. Yan, Q. Zhou, M. Vincent, Y. Deng, J. Yu, J. Xu, T. Xu, T. Tang, L. Bian, Y. X. J. Wang, K. Kostarelos, L. Zhang. Multifunctional biohybrid magnetite microrobots for imaging-guided therapy. Sci. Robot., 2, eaaq1155(2017).
[14] B. Wang, K. F. Chan, K. Yuan, Q. Wang, X. Xia, L. Yang, H. Ko, Y. J. Wang, J. Jao, Y. Sung, P. Wai, Y. Chiu, L. Zhang. Endoscopy-assisted magnetic navigation of biohybrid soft microrobots with rapid endoluminal delivery and imaging. Sci. Robot., 6, eabd2813(2021).
[15] Q. Wang, K. F. Chan, K. Schweizer, X. Du, D. Jin, S. C. H. Yu, B. J. Nelson, L. Zhang. Ultrasound Doppler-guided real-time navigation of a magnetic microswarm for active endovascular delivery. Sci. Adv., 7, eabe5914(2021).
[16] Q. Wang, L. Zhang. External power-driven microrobotic swarm: from fundamental understanding to imaging-guided delivery. ACS Nano., 15, 149(2021).
[17] Q. Wang, L. Zhang. Ultrasound imaging and tracking of micro/nanorobots: from individual to collectives. IEEE Open J. Nanotechnol., 1, 6(2020).
[18] Q. Wang, L. Yang, J. Yu, P. W. Y. Chiu, Y. P. Zheng, L. Zhang. Real-time magnetic navigation of a rotating colloidal microswarm under ultrasound guidance. IEEE Trans. Biomed. Eng., 67, 3403(2020).
[19] S. Jeong, H. Choi, C. Lee, G. Go, D. S. Sim, K. S. Lim, M. H. Jeong, S. Y. Ko, J. Park, S. Park. Therapeutic intravascular microrobot through compensation of resistance and mutual inductance in electromagnetic actuation system. Int. J. Control. Autom. Syst., 13, 1465(2015).
[20] S. Pané, J. Puigmartí-Luis, C. Bergeles, X.-Z. Chen, E. Pellicer, J. Sort, V. Počepcová, A. Ferreira, B. J. Nelson. Imaging technologies for biomedical micro- and nanoswimmers. Adv. Mater. Technol., 4, 1800575(2019).
[21] M. Medina-Sánchez, O. G. Schmidt. Medical microbots need better imaging and control. Nature, 545, 406(2017).
[22] D. Li, C. Liu, Y. Yang, L. Wang, Y. Shen. Micro-rocket robot with all-optic actuating and tracking in blood. Light Sci. Appl., 9, 84(2020).
[23] T. Wei, J. Liu, D. Li, S. Chen, Y. Zhang, J. Li, L. Fan, Z. Guan, C. Lo, L. Wang, K. Man, D. Sun. Development of magnet-driven and image-guided degradable microrobots for the precise delivery of engineered stem cells for cancer therapy. Small, 16, 1906908(2020).
[24] L. V. Wang, J. Yao. A practical guide to photoacoustic tomography in the life sciences. Nat. Methods, 13, 627(2016).
[25] S. Manohar, D. Razansky. Photoacoustics: a historical review. Adv. Opt. Photon., 8, 586(2016).
[26] M. Xu, L. V. Wang. Photoacoustic imaging in biomedicine. Rev. Sci. Instrum., 77, 041101(2006).
[27] T. Feng, Y. Zhu, Y. Xie, D. Ta, J. Yuan, Q. Cheng. Feasibility study for bone health assessment based on photoacoustic imaging method. Chin. Opt. Lett., 18, 121704(2020).
[28] A. Danielli, K. I. Maslov, A. Garcia-Uribe, A. M. Winkler, C. Li, L. Wang, Y. Chen, G. W. Dorn, L. V. Wang. Label-free photoacoustic nanoscopy. J. Biomed. Opt., 19, 086006(2014).
[29] C. Liu, Y. Liang, L. Wang. Optical-resolution photoacoustic microscopy of oxygen saturation with nonlinear compensation. Biomed. Opt. Express, 10, 3061(2019).
[30] L. Lin, P. Hu, J. Shi, C. M. Appleton, K. Maslov, L. Li, R. Zhang, L. V. Wang. Single-breath-hold photoacoustic computed tomography of the breast. Nat. Commun., 9, 2352(2018).
[31] Y. Matsumoto, Y. Asao, A. Yoshikawa, H. Sekiguchi, M. Takada, M. Furu, S. Saito, M. Kataoka, H. Abe, T. Yagi, K. Togashi, M. Toi. Label-free photoacoustic imaging of human palmar vessels: a structural morphological analysis. Sci. Rep., 8, 786(2018).
[32] A. P. Jathoul, J. Laufer, O. Ogunlade, B. Treeby, B. Cox, E. Zhang, P. Johnson, A. R. Pizzey, B. Philip, T. Marafioti, M. F. Lythgoe, R. B. Pedley, M. A. Pule, P. Beard. Deep in vivo photoacoustic imaging of mammalian tissues using a tyrosinase-based genetic reporter. Nat. Photon., 9, 239(2015).
[33] J. Chen, Y. Zhang, X. Li, J. Zhu, D. Li, S. Li, C.-S. Lee, L. Wang. Confocal visible/NIR photoacoustic microscopy of tumors with structural, functional, and nanoprobe contrasts. Photon. Res., 8, 1875(2020).
[34] C. Liu, Y. Liang, L. Wang. Single-shot photoacoustic microscopy of hemoglobin concentration, oxygen saturation, and blood flow in sub-microseconds. Photoacoustics, 17, 100156(2020).
[35] C. Liu, J. Chen, Y. Zhang, J. Zhu, L. Wang. Five-wavelength optical-resolution photoacoustic microscopy of blood and lymphatic vessels. Adv. Photon., 3, 016002(2021).
[36] L. Lin, J. Yao, L. Li, L. V. Wang. In vivo photoacoustic tomography of myoglobin oxygen saturation. J. Biomed. Opt., 21, 061002(2015).
[37] B. Wang, J. L. Su, J. Amirian, S. H. Litovsky, R. Smalling, S. Emelianov. Detection of lipid in atherosclerotic vessels using ultrasound-guided spectroscopic intravascular photoacoustic imaging. Opt. Express, 18, 4889(2010).
[38] C. Yin, G. Wen, C. Liu, B. Yang, S. Lin, J. Huang, P. Zhao, S. H. D. Wong, K. Zhang, X. Chen, G. Li, X. Jiang, J. Huang, K. Pu, L. Wang, L. Bian. Organic semiconducting polymer nanoparticles for photoacoustic labeling and tracking of stem cells in the second near-infrared window. ACS Nano., 12, 12201(2018).
[39] Y. Dai, X. Yu, J. Wei, F. Zeng, Y. Li, X. Yang, Q. Luo, Z. Zhang. Metastatic status of sentinel lymph nodes in breast cancer determined with photoacoustic microscopy via dual-targeting nanoparticles. Light Sci. Appl., 9, 164(2020).
[40] H. Fang, K. Maslov, L. V. Wang. Photoacoustic Doppler effect from flowing small light-absorbing particles. Phys. Rev. Lett., 99, 184501(2007).
[41] J. Yao, K. I. Maslov, Y. Shi, L. A. Taber, L. V. Wang. In vivo photoacoustic imaging of transverse blood flow by using Doppler broadening of bandwidth. Opt. Lett., 35, 1419(2010).
[42] L. Xie, X. Pang, X. Yan, Q. Dai, H. Lin, J. Ye, Y. Cheng, Q. Zhao, X. Ma, X. Zhang, G. Liu, X. Chen. Photoacoustic imaging-trackable magnetic microswimmers for pathogenic bacterial infection treatment. ACS Nano., 14, 2880(2020).
[43] L. Li, L. Zhu, C. Ma, L. Lin, J. Yao, L. Wang, K. Maslov, R. Zhang, W. Chen, J. Shi, L. V. Wang. Single-impulse panoramic photoacoustic computed tomography of small-animal whole-body dynamics at high spatiotemporal resolution. Nat. Biomed. Eng., 1, 0071(2017).
[44] P. Zhang, L. Li, L. Lin, J. Shi, L. V. Wang. In vivo superresolution photoacoustic computed tomography by localization of single dyed droplets. Light Sci. Appl., 8, 36(2019).
[45] W. Choi, C. Kim. Toward in vivo translation of super-resolution localization photoacoustic computed tomography using liquid-state dyed droplets. Light Sci. Appl., 8, 57(2019).
[46] J. Yao, L. Wang, J. M. Yang, K. I. Maslov, T. T. W. Wong, L. Li, C. H. Huang, J. Zou, L. V. Wang. High-speed label-free functional photoacoustic microscopy of mouse brain in action. Nat. Methods, 12, 407(2015).
[47] Y. Li, T. T. W. Wong, J. Shi, H. C. Hsu, L. V. Wang. Multifocal photoacoustic microscopy using a single-element ultrasonic transducer through an ergodic relay. Light Sci. Appl., 9, 135(2020).
[48] M. Chen, H. J. Knox, Y. Tang, W. Liu, L. Nie, J. Chan, J. Yao. Simultaneous photoacoustic imaging of intravascular and tissue oxygenation. Opt. Lett., 44, 3773(2019).
[49] Y. Liang, L. Jin, B.-O. Guan, L. Wang. 2 MHz multi-wavelength pulsed laser for functional photoacoustic microscopy. Opt. Lett., 42, 1452(2017).
[50] J. Kim, J. Y. Kim, S. Jeon, J. W. Baik, S. H. Cho, C. Kim. Super-resolution localization photoacoustic microscopy using intrinsic red blood cells as contrast absorbers. Light Sci. Appl., 8, 103(2019).
[51] E. Vienneau, W. Liu, J. Yao. Dual-view acoustic-resolution photoacoustic microscopy with enhanced resolution isotropy. Opt. Lett., 43, 4413(2018).
[52] P. K. Upputuri, M. Pramanik. Recent advances toward preclinical and clinical translation of photoacoustic tomography: a review. J. Biomed. Opt., 22, 041006(2016).
[53] L. V. Wang, S. Hu. Photoacoustic tomography: in vivo imaging from organelles to organs. Science, 335, 1458(2012).
[54] J. Yao, A. A. Kaberniuk, L. Li, D. M. Shcherbakova, R. Zhang, L. Wang, G. Li, V. V. Verkhusha, L. V. Wang. Multiscale photoacoustic tomography using reversibly switchable bacterial phytochrome as a near-infrared photochromic probe. Nat. Methods, 13, 67(2015).
[55] X. Wang, S. Yang. Imaging of human wrist joint by a flexible-transducer-based morphological-adaptive photoacoustic tomography: a feasibility study. Chin. Opt. Lett., 17, 091701(2019).
[56] G. Li, L. Li, L. Zhu, J. Xia, L. V. Wang. Multiview Hilbert transformation for full-view photoacoustic computed tomography using a linear array. J. Biomed. Opt., 20, 066010(2015).
[57] L. Wang, G. Li, J. Xia, L. V. Wang. Ultrasonic-heating-encoded photoacoustic tomography with virtually augmented detection view. Optica, 2, 307(2015).
[58] L. Lin, P. Hu, X. Tong, S. Na, R. Cao, X. Yuan, D. C. Garrett, J. Shi, K. Maslov, L. V. Wang. High-speed three-dimensional photoacoustic computed tomography for preclinical research and clinical translation. Nat. Commun., 12, 882(2021).
[59] K. Huda, C. Wu, J. G. Sider, C. L. Bayer. Spherical-view photoacoustic tomography for monitoring in vivo placental function. Photoacoustics, 20, 100209(2020).
[60] Y. Zhang, L. Wang. Video-rate ring-array ultrasound and photoacoustic tomography. IEEE Trans. Med. Imaging., 39, 4369(2020).
[61] H. Estrada, A. Ozbek, J. Robin, S. Shoham, D. Razansky. Spherical array system for high-precision transcranial ultrasound stimulation and optoacoustic imaging in rodents. IEEE Trans. Ultrason. Ferroelectr. Freq. Control., 68, 107(2021).
[62] M. Heijblom, W. Steenbergen, S. Manohar. Clinical photoacoustic breast imaging: the Twente experience. IEEE Pulse, 6, 42(2015).
[63] F. Zheng, X. Zhang, C. T. Chiu, B. L. Zhou, K. K. Shung, H. F. Zhang, S. Jiao. Laser-scanning photoacoustic microscopy with ultrasonic phased array transducer. Biomed. Opt. Express, 3, 2694(2012).
[64] S. Li, Q. Deng, Y. Zhang, X. Li, G. Wen, X. Cui, Y. Wan, Y. Huang, J. Chen, Z. Liu, L. Wang, C. S. Lee. Rational design of conjugated small molecules for superior photothermal theranostics in the NIR-II biowindow. Adv. Mater., 32, 2001146(2020).
[65] G. Wen, X. Li, Y. Zhang, X. Han, X. Xu, C. Liu, K. W. Y. Chan, C. S. Lee, C. Yin, L. Bian, L. Wang. Effective phototheranostics of brain tumor assisted by near-infrared-II light-responsive semiconducting polymer nanoparticles. ACS Appl. Mater. Interfaces., 12, 33492(2020).
[66] M. Zha, X. Lin, J. S. Ni, Y. Li, Y. Zhang, X. Zhang, L. Wang, K. Li. An ester-substituted semiconducting polymer with efficient nonradiative decay enhances NIR-II photoacoustic performance for monitoring of tumor growth. Angew. Chemie–Int. Ed., 59, 23268(2020).
[67] J. Zhang, G. Wen, W. Wang, K. Cheng, Q. Guo, S. Tian, C. Liu, H. Hu, Y. Zhang, H. Zhang, L. Wang, H. Sun. Controllable cleavage of C–N bond-based fluorescent and photoacoustic dual-modal probes for the detection of H2S in living mice. ACS Appl. Bio Mater., 4, 2020(2021).
[68] J. Xia, C. Kim, J. F. Lovell. Opportunities for photoacoustic-guided drug delivery. Curr. Drug Targets., 16, 571(2015).
[69] N. Gandhi, M. Allard, S. Kim, P. Kazanzides, M. A. L. Bell. Photoacoustic-based approach to surgical guidance performed with and without a da Vinci robot. J. Biomed. Opt., 22, 121606(2017).
[70] Z. Wu, L. Li, Y. Yang, P. Hu, Y. Li, S. Y. Yang, L. V. Wang, W. Gao. A microrobotic system guided by photoacoustic computed tomography for targeted navigation in intestines in vivo. Sci. Robot, 4, eaax0613(2019).
[71] L. Labanieh, R. G. Majzner, C. L. Mackall. Programming CAR-T cells to kill cancer. Nat. Biomed. Eng., 2, 377(2018).
[72] A. Aziz, M. Medina-Sánchez, J. Claussen, O. G. Schmidt. Real-time optoacoustic tracking of single moving micro-objects in deep phantom and ex vivo tissues. Nano Lett., 19, 6612(2019).
[73] Y. Yan, W. Jing, M. Mehrmohammadi. Photoacoustic imaging to track magnetic-manipulated micro-robots in deep tissue. Sensors, 20, 2816(2020).
[74] G. S. Jeng, M. L. Li, M. W. Kim, S. J. Yoon, J. J. Pitre, D. S. Li, I. Pelivanov, M. O’Donnell. Real-time interleaved spectroscopic photoacoustic and ultrasound (PAUS) scanning with simultaneous fluence compensation and motion correction. Nat. Commun., 12, 716(2021).
[75] H. Su. Optical-resolution photoacoutic microscopy(2010).
[76] K. Maslov, H. F. Zhang, S. Hu, L. V. Wang. Optical-resolution photoacoustic microscopy for in vivo imaging of single capillaries. Opt. Lett., 33, 929(2008).
[77] S. Hu, K. Maslov, L. V. Wang. Second-generation optical-resolution photoacoustic microscopy with improved sensitivity and speed. Opt. Lett., 36, 1134(2011).
[78] Y. Liang, J.-W. Liu, L. Jin, B.-O. Guan, L. Wang. Fast-scanning photoacoustic microscopy with a side-looking fiber optic ultrasound sensor. Biomed. Opt. Express, 9, 5809(2018).
[79] B. Rao, K. Maslov, A. Danielli, R. Chen, K. K. Shung, Q. Zhou, L. V. Wang. Real-time four-dimensional optical-resolution photoacoustic microscopy with Au nanoparticle-assisted subdiffraction-limit resolution. Opt. Lett., 36, 1137(2011).
[80] W. Qin, T. Jin, H. Guo, L. Xi. Large-field-of-view optical resolution photoacoustic microscopy. Opt. Express, 26, 4271(2018).
[81] C. Zhang, H. Zhao, S. Xu, N. Chen, K. Li, X. Jiang, L. Liu, Z. Liu, L. Wang, K. K. Y. Wong, J. Zou, C. Liu, L. Song. Multiscale high-speed photoacoustic microscopy based on free-space light transmission and a MEMS scanning mirror. Opt. Lett., 45, 4312(2020).
[82] J. Lee, S. Han, D. Seong, J. Lee, S. Park, R. Eranga Wijesinghe, M. Jeon, J. Kim. Fully waterproof two-axis galvanometer scanner for enhanced wide-field optical-resolution photoacoustic microscopy. Opt. Lett., 45, 865(2020).
[83] L. Wang, K. Maslov, L. V. Wang. Single-cell label-free photoacoustic flowoxigraphy in vivo. Proc. Natl. Acad. Sci. U. S. A., 110, 5759(2013).
[84] L. Wang, K. Maslov, J. Yao, B. Rao, L. V. Wang. Fast voice-coil scanning optical-resolution photoacoustic microscopy. Opt. Lett., 36, 139(2011).
[85] J. Chen, Y. Zhang, L. He, Y. Liang, L. Wang. Wide-field polygon-scanning photoacoustic microscopy of oxygen saturation at 1-MHz A-line rate. Photoacoustics., 20, 100195(2020).
[86] J. Y. Kim, C. Lee, K. Park, S. Han, C. Kim. High-speed and high-SNR photoacoustic microscopy based on a galvanometer mirror in non-conducting liquid. Nat. Publ. Gr., 6, 34803(2016).
[87] J. Y. Kim, C. Lee, K. Park, G. Lim, C. Kim. Fast optical-resolution photoacoustic microscopy using a 2-axis water-proofing MEMS scanner. Sci. Rep., 5, 7932(2015).
[88] B. Lan, W. Liu, Y. Wang, J. Shi, Y. Li, S. Xu, H. Sheng, Q. Zhou, J. Zou, U. Hoffmann, W. Yang, J. Yao. High-speed widefield photoacoustic microscopy of small-animal hemodynamics. Biomed. Opt. Express, 9, 4689(2018).
