Optical phase conjugation (OPC) for focusing light through/inside biological tissue

Chengmingyue Li

doi:10.3788/irla201948.0702001

[1] Fisher R. Optical Phase Conjugation[M]. San Diego: Academic Press, 1983.

[2] He G S. Optical phase conjugation: principles, techniques, and applications[J]. Progress in Quantum Electronics, 2002, 26: 131-191.

[3] Leith E N, Upatnieks J. Holographic imagery through diffusing media[J]. Journal of the Optical Society of America, 1966, 56: 523-523.

[4] Goodman J W, Huntley W H, Jackson D W, et al. Wavefront-reconstruction imaging through random media[J]. Appl Phys Lett, 1966, 8: 311-313.

[5] Pepper D M, Fekete D, Yariv A. Observation of amplified phase-conjugate reflection and optical parametric oscillation by degenerate 4-wave mixing in a transparent medium[J].Appl Phys Lett, 1978, 33: 41-44.

[6] Auyeung J, Fekete D, Pepper D, et al. A theoretical and experimental investigation of the modes of optical resonators with phase-conjugate mirrors[J]. IEEE J Quantum Electron, 1979, 15: 1180-1188.

[7] Levenson M D. High-resolution imaging by wave-front conjugation[J]. Opt Lett, 1980, 5: 182-184.

[8] Sun X, Zhou Z, Li Y, et al. Holographic associative memory using a coherently induced double phase conjugate mirror[J]. Opt Eng, 1996, 35: 2153-2157.

[9] Yariv A. Phase conjugate optics and real-time holography[J].IEEE J Quantum Electron, 1978, 14: 650-660.

[10] Dunning G J, Lind R C. Demonstration of image transmission through fibers by optical phase conjugation[J]. Opt Lett, 1982, 7: 558-560.

[11] Yariv A, Fekete D, Pepper D M. Compensation for channel dispersion by nonlinear optical phase conjugation[J]. Opt Lett, 1979, 4: 52-54.

[12] Gower M C, Caro R G. KrF laser with a phase-conjugate Brillouin mirror[J]. Opt Lett, 1982, 7: 162-164.

[13] Xu X, Liu H, Wang L V. Time-reversed ultrasonically encoded optical focusing into scattering media[J]. Nat Photonics, 2011, 5: 154-157.

[14] Horstmeyer R, Ruan H, Yang C. Guidestar-assisted wavefront-shaping methods for focusing light into biological tissue[J].Nat Photonics, 2015, 9: 563-571.

[15] Wang Lihong, Wu H. Biomedical Optics: Principles and Imaging[M]. Hoboken: John Wiley & Sons, 2007.

[16] Yaqoob Z, Psaltis D, Feld M S, et al. Optical phase conjugation for turbidity suppression in biological samples[J]. Nat Photonics, 2008, 2: 110-115.

[17] Yariv A, Pepper D M. Amplified reflection, phase conjugation, and oscillation in degenerate four-wave mixing[J]. Opt Lett, 1977, 1: 16-18.

[18] Wang V, Giuliano C R. Correction of phase aberrations via stimulated Brillouin scattering[J]. Opt Lett, 1978, 2: 4-6.

[19] Tomov I V, Fedosejevs R, McKen D C C, et al. Phase conjugation and pulse compression of KrF-laser radiation by stimulated Raman scattering[J]. Opt Lett, 1983, 8: 9-11.

[20] Kogelnik H. Holographic image projection through inhomogeneous media[J]. Bell Syst Tech J, 1965, 44: 2451-2455.

[21] McDowell E J, Cui M, Vellekoop I M, et al. Turbidity suppression from the ballistic to the diffusive regime in biological tissues using optical phase conjugation[J]. Journal of Biomedical Optics, 2010, 15(2): 025004.

[22] Cui M, McDowell E J, Yang C. An in vivo study of turbidity suppression by optical phase conjugation (TSOPC) on rabbit ear[J]. Opt Express, 2010, 18: 25-30.

[23] Lai P, Xu X, Liu H, et al. Time-reversed ultrasonically encoded optical focusing in biological tissue[J]. Journal of Biomedical Optics, 2012, 17(3): 036001.

[24] Yang Q, Xu X, Lai P, et al. Time-reversed ultrasonically encoded optical focusing using two ultrasonic transducers for improved ultrasonic axial resolution[J]. Journal of Biomedical Optics, 2013, 18(11): 110502.

[25] Lai P, Suzuki Y, Xu X, et al. Focused fluorescence excitation with time-reversed ultrasonically encoded light and imaging in thick scattering media[J]. Laser Physics Letters, 2013, 10(7): 075604.

[26] Liu Y, Lai P, Ma C, et al. Optical focusing deep inside dynamic scattering media with near-infrared time-reversed ultrasonically encoded (TRUE) light[J]. Nature Communications, 2015, 6: 5904.

[27] Ma C, Xu X, Wang L V. Analog time-reversed ultrasonically encoded light focusing inside scattering media with a 33 000× optical power gain[J]. Scientific Reports, 2015, 5: 8896.

[28] Suzuki Y, Xu X, Lai P, et al. Energy enhancement in time-reversed ultrasonically encoded optical focusing using a photorefractive polymer[J]. Journal of Biomedical Optics, 2012, 17(8): 80507.

[29] Pang G, Liu H, Hou P, et al. Optical phase conjugation of diffused light with infinite gain by using gated two-color photorefractive crystal LiNbO3: Cu: Ce[J]. Appl Opt, 2018, 57: 2675-2678.

[30] Cui M, Yang C. Implementation of a digital optical phase conjugation system and its application to study the robustness of turbidity suppression by phase conjugation[J]. Opt Express, 2010, 18: 3444-3455.

[31] Jang M, Ruan H, Zhou H, et al. Method for auto-alignment of digital optical phase conjugation systems based on digital propagation[J]. Opt Express, 2014, 22: 14054-14071.

[32] Hemphill A S, Shen Y, Hwang J, et al. High-speed alignment optimization of digital optical phase conjugation systems based on autocovariance analysis in conjunction with orthonormal rectangular polynomials[J]. Journal of Biomedical Optics, 2018, 24(3): 031004.

[33] Azimipour M, Atry F, Pashaie R. Calibration of digital optical phase conjugation setups based on orthonormal rectangular polynomials[J]. Appl Opt, 2016, 55: 2873-2880.

[34] Hillman T R, Yamauchi T, Choi W, et al. Digital optical phase conjugation for delivering two-dimensional images through turbid media[J]. Scientific Reports, 2013, 3: 1909.

[35] Shen Y, Liu Y, Ma C, et al. Focusing light through biological tissue and tissue-mimicking phantoms up to 9.6 cm in thickness with digital optical phase conjugation[J]. Journal of Biomedical Optics, 2016, 21(8): 085001.

[36] Liu Y, Shen Y, Ruan H, et al. Time-reversed ultrasonically encoded optical focusing through highly scattering ex vivo human cataractous lenses[J]. Journal of Biomedical Optics, 2018, 23(1): 010501.

[37] Jang M, Ruan H, Vellekoop I M, et al. Relation between speckle decorrelation and optical phase conjugation (OPC)-based turbidity suppression through dynamic scattering media: a study on in vivo mouse skin[J]. Biomedical Optics Express, 2015, 6: 72-85.

[38] Wang D, Zhou E H, Brake J, et al. Focusing through dynamic tissue with millisecond digital optical phase conjugation[J]. Optica, 2015, 2(8): 728-735.

[39] Wang Y M, Judkewitz B, DiMarzio C A, et al. Deep-tissue focal fluorescence imaging with digitally time-reversed ultrasound-encoded light[J]. Nature Communications, 2012, 3: 928.

[40] Si K, Fiolka R, Cui M. Fluorescence imaging beyond the ballistic regime by ultrasound-pulse-guided digital phase conjugation[J]. Nat Photonics, 2012, 6: 657-661.

[41] Si K, Fiolka R, Cui M. Breaking the spatial resolution barrier via iterative sound-light interaction in deep tissue microscopy[J]. Scientific Reports, 2012, 2: 748.

[42] Ruan H, Jang M, Judkewitz B, et al. Iterative time-reversed ultrasonically encoded light focusing in backscattering mode[J]. Scientific Reports, 2014, 4: 7156.

[43] Judkewitz B, Wang Y M, Horstmeyer R, et al. Speckle-scale focusing in the diffusive regime with time reversal of variance-encoded light (TROVE)[J]. Nat Photonics, 2013, 7: 300-305.

[44] Hsieh C L, Pu Y, Grange R, et al. Imaging through turbid layers by scanning the phase conjugated second harmonic radiation from a nanoparticle[J]. Opt Express, 2010, 18: 20723-20731.

[45] Vellekoop I M, Cui M, Yang C. Digital optical phase conjugation of fluorescence in turbid tissue[J]. Appl Phys Lett, 2012, 101(8): 81108.

[46] Ruan H, Jang M, Yang C. Optical focusing inside scattering media with time-reversed ultrasound microbubble encoded light[J]. Nature Communications, 2015, 6: 8968.

[47] Ruan H, Haber T, Liu Y, et al. Focusing light inside scattering media with magnetic-particle-guided wavefront shaping[J]. Optica, 2017, 4: 1337-1343.

[48] Ma C, Xu X, Liu Y, et al. Time-reversed adapted-perturbation (TRAP) optical focusing onto dynamic objects inside scattering media[J]. Nat Photonics, 2014, 8: 931-936.

[49] Zhou E H, Ruan H, Yang C, et al. Focusing on moving targets through scattering samples[J]. Optica, 2014, 1: 227-232.

[50] Ruan H, Brake J, Robinson J E, et al. Deep tissue optical focusing and optogenetic modulation with time-reversed ultrasonically encoded light[J]. Science Advances, 2017, 3: eaao5520.

[51] Park J-H, Yu Z, Lee K, et al. Perspective: Wavefront shaping techniques for controlling multiple light scattering in biological tissues: Toward in vivo applications[J]. APL Photonics, 2018, 3: 100901.

[52] Shen Y, Liu Y, Ma C, et al. Sub-Nyquist sampling boosts targeted light transport through opaque scattering media[J].Optica, 2017, 4: 97-102.

[53] Hemphill A S, Shen Y, Liu Y, et al. High-speed single-shot optical focusing through dynamic scattering media with full-phase wavefront shaping[J]. Appl Phys Lett, 2017, 111: 221109.

[54] Klein M B. Beam coupling in undoped GaAs at 1.06 μm using the photorefractive effect[J]. Opt Lett, 1984, 9: 350-352.

[55] Liu Y, Ma C, Shen Y, et al. Focusing light inside dynamic scattering media with millisecond digital optical phase conjugation[J]. Optica, 2017, 4: 280-288.

[56] Hemphill A S, Tay J W, Wang L V. Hybridized wavefront shaping for high-speed, high-efficiency focusing through dynamic diffusive media[J]. Journal of Biomedical Optics, 2016, 21(12): 121502.

[57] Liu Y, Ma C, Shen Y, et al. Bit-efficient, sub-millisecond wavefront measurement using a lock-in camera for time-reversal based optical focusing inside scattering media[J]. Opt Lett, 2016, 41: 1321-1324.

[58] Ma C, Zhou F, Liu Y, et al. Single-exposure optical focusing inside scattering media using binarized time-reversed adapted perturbation[J]. Optica, 2015, 2: 869-876.