• Journal of Inorganic Materials
  • Vol. 38, Issue 1, 3 (2023)
Yanyan LI1、2, Yusi PENG1、2, Chenglong LIN1、2, Xiaoying LUO3, Zheng TENG4、*, Xi ZHANG4, Zhengren HUANG1、2, and Yong YANG1、2、*
Author Affiliations
  • 11. State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China
  • 22. College of Materials Science and Opto-Electronics Engineering, University of Chinese Academy of Sciences, Beijing 100049, China
  • 33. State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200032, China
  • 44. Shanghai Provincial Center for Disease Control and Prevention, Shanghai 200336, China
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    DOI: 10.15541/jim20220218 Cite this Article
    Yanyan LI, Yusi PENG, Chenglong LIN, Xiaoying LUO, Zheng TENG, Xi ZHANG, Zhengren HUANG, Yong YANG. Nanomaterials and Biosensing Technology for the SARS-CoV-2 Detection[J]. Journal of Inorganic Materials, 2023, 38(1): 3 Copy Citation Text show less

    Abstract

    The outbreak of corona virus disease 2019 (COVID-19) has aroused great attention around the world. SARS-CoV-2 possesses characteristics of faster transmission, immune escape, and occult transmission by many mutation, which caused still grim situation of prevention and control. Early detection and isolation of patients are still the most effective measures at present. So, there is an urgent need for new rapid and highly sensitive testing tools to quickly identify infected patients as soon as possible. This review briefly introduces general characteristics of SARS-CoV-2, and provides recentl overview and analysis based on different detection methods for nucleic acids, antibodies, antigens as detection target. Novel nano-biosensors for SARS-CoV-2 detection are analyzed based on optics, electricity, magnetism, and visualization. In view of the advantages of nanotechnology in improving detection sensitivity, specificity and accuracy, the research progress of new nano-biosensors is introduced in detail, including SERS-based biosensors, electrochemical biosensors, magnetic nano-biosensors and colorimetric biosensors. Functions and challenges of nano-materials in construction of new nano-biosensors are discussed, which provides ideas for the development of various coronavirus biosensing technologies for nanomaterial researchers.
    Yanyan LI, Yusi PENG, Chenglong LIN, Xiaoying LUO, Zheng TENG, Xi ZHANG, Zhengren HUANG, Yong YANG. Nanomaterials and Biosensing Technology for the SARS-CoV-2 Detection[J]. Journal of Inorganic Materials, 2023, 38(1): 3
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