The strengthen treatment of Inconel X-50 nickel-based alloys are performed by laser peening (LP) with different pulse energies. The hot-corrosion behavior of specimens under different conditions is studied, and the mechanism of enhancement of hot-corrosion-resistance property by LP is discussed. The results show that the corrosion rate of specimens after LP processing is obviously lower than that of the untreated specimens, and the higher the pulse energy is, the lower the corrosion rate of specimens after LP processing is. The untreated specimens exhibit two corrosion layers after hot-corrosion for 60 h where the outer corrosion layer is seriously corroded and thus the phenomenon of breaking and stripping off arises. The specimens after LP processing only appear an internal oxide layer after hot-corrosion for 60 h. The LP-induced residual stress layer effectively avoids the rupture of oxide films.