Experimental results of excised wounds in the skin of 71 rabbits irradiated respectively by lasers are reported with emphasis on morphological and histologic investigation.No effect was observed for He-Cd laser,while obvious effect was manifested for He-Ne laser and CO2 laser. Preliminary conclusion is that the mechanism for promoting the healing of wounds may be the circulation improvement of blood and lymph,as well as stimulated generation of fibrOblasts.