The Raman spectra of 35 stone samples (13 Shoushan stones and 22 Laos stones) are measured by a self-developed portable Raman spectrometer Hx-Spec, which is excited by a 785 nm diode laser and the spectrum range is 200-2700 cm-1 with a resolution of 6 cm-1. A multioariate model is established by combining the principal component analysis (PCA) and the linear discriminant analysis (LDA), a discrimination sensitivity of 86.7% and a specificity of 100% are achieved in separating Laos stone from Shoushan stone, while the performance of corresponding receiver operating characteristic (ROC) curve is 0.977. Besides, a discriminant accuracy achieves 87.5% after 8 new samples are added as a validation. These results demonstrate that the utility of portable Raman spectrometer combined with chemometrics provides a new strategy to discriminate the Shoushan and Laos stones.