The large view, polarized and multispectral camera detects the angular and polarized two more dimensional information than a traditional optical multi-spectral camera, and has great advances especially in aerosol remote sensing. So, near the year of 2020, a number of satellites loading multi-angle and polarized camera would be launched in different countries. As a high quantitative sensor, its in-flight calibration has always been attractive. Due to the lack of onboard calibration instrument and the low spatial resolution, the natural scenery targets are selected to be vicarious optic references for the calibration. Multi-angel polarized camera has several parameters to be calibrated. The radiometric calibration of polarized camera includes intensity and polarization parameters. Different calibration parameters are calibrated using many natural targets by many methods which are developed in parallel. The Gaofen-5 launched in 2018 is the first satellite loading polarized sensor of China, also the only operational satellite in the world this time. In view of many new polarized camera aerospace plans in European and American countries and China, the vicarious calibration for polarized camera is necessary to overview. In this paper, the optical structure and the spectral settings of the large view, polarized and multispectral camera are presented. The optical transfer model of camera is introduced. The in-flight calibration theory and method of each camera parameter is classified into three categories including absolute radiometric intensity, relative radiometric intensity and polarization. For a specified calibration coefficient, the natural target and calibration flow are introduced for the in-flight calibration. The method system is formed for the in-flight radiometric calibration of the large view, polarized and multispectral camera. Also, the general validation methods of calibration are concluded. The in-flight calibration of the new large view, polarized and multispectral camera will inherit the original research and use special natural scenery to carry out calibration. In the same kind of future remote sensing camera, new style in-flight radiometric calibration will be based on the instruments and its calibrator onboard the same satellite platform, ground-based artificial optical source and others. China, Europe and America have planned some future polarized camera, jointly considering the research basis of authors, preliminary design and prospects for the future on-orbit calibration method are given. A polarized multispectral camera mainly serves the remote sensing monitoring of atmospheric particulate matter, which is very important for the atmospheric environment problems currently concerned in China. A continuous in-flight calibration can ensure the accuracy of satellite remote sensing retrieved products. This overview of in-flight calibration research and the preliminary design for the future calibration method will provide method and model references for the remote sensing application system of the planned satellite.