With the rapid development of modern technology, high-precision absolute distance measurement is playing an important role in many applications, such as scientific research, aviation and industry measurement. Among the above various measurement methods, how to realize higher-accuracy, larger-scale, and faster-speed measurement is particularly important. In the traditional technique for long-distance measurement, the emergence of optical frequency comb (OFC) provides a breakthrough technology for accurately measuring the absolute value of distance. The OFC can be considered as a multi-wavelength source,whose phase and repetition rate are locked. The OFC is a very useful light source that can provide phase-coherent link between microwave and optical domain, which has been used as a source in various distance measurement schemes that can reach an extraordinary measurement precision and accuracy. A variety of laser ranging methods such as dual-comb interferometry and dispersive interferometer based on femtosecond laser have been applied to the measuring of absolute distance.In this paper, the factors affecting the resolution and the non-ambiguous range of spectral interferometry ranging using OFC are particularly discussed. We also analyze the systematic errors and the limitations of traditional transform methods based on Fourier transform, which can conduce to the subsequent research.To address the problem caused by low resolution and unequal frequency interval, we propose a data processing method referred to as equal frequency interval resampling. The proposed method is based on cubic spline interpolation and can solve the error caused by the frequency spectrum broadening with the increase of distance. Moreover, we propose a new method based on least square fitting to calibrate the error introduced by the low resolution of interferometry spectrum obtained with fast Fourier transform (FFT). With the proposed method, the simulation results show that the systematic error is less than 0.2 μm in the non-ambiguity range and the system resolution is greatly improved. Finally, anabsolute distance measurement system based on Michelson interferometer is built to verify theproposed method. The measurement results compared with those obtained by using a high-precision commercial He-Ne laser interferometer show that the distance measurement accuracy is lower than 3 μm at any distancewithin the non-ambiguity range. The experimental results demonstrate that our data processing algorithm is able to increase the accuracy of dispersive interferometry ranging with OFC.