The simulating experiment on hydro-acoustic effect of high energy charged particles by Q-switehed pulsed laser beams has been made. The influence of heat pulse waveform on the time structure and the amplitude of acoustic signls has been also observed and studied by means of a non-Q-switched pulsed laser. A comparision between our experimental results and the data of hydro-acoustic effect of charged particle beams generated by accelerator shows that the main experimental results from these two methods are consistent. Further application of pulsed laser technique to the study of high energy physics and cosmic ray physics are discussed.