The radiation force of highly focused hybridly polarized beams on a Rayleigh particle was theoretically studied and the expression was derived.The influence of numerical apertures of an objective and radial coefficient on the radiation force distribution and the longitudinal intensity distribution on the focal plane were numerically simulated.The numerical results show that radiation forces by highly focused hybridly polarized vector beams can be used to trap three-dimensional Rayleigh particles, and the trapping property is affected by the numerical aperture and radial coefficient obviously. Copious experimental data indicate that it can be done only when the radial coefficient is greater than 3.