MITOCHONDRIAL FUNCTION AND TISSUE VIABILITY IN VIVO: FROM ANIMAL EXPERIMENTS TO CLINICAL APPLICATIONS. FORTY YEARS OF FRUITFUL COLLABORATION WITH BRITTON CHANCE

AVRAHAM MAYEVSKY

doi:10.1142/s1793545811001654

[1] A. Mayevsky, B. Chance, "A new long-term method for the measurement of NADH fluorescence in intact rat brain with implanted cannula," Int. Symp. Oxygen Transport to Tissue, Adv. Exp. Med. Biol., pp. 239-244, Plenum Press, New York (1973).

[2] B. Chance, N. Oshino, T. Sugano, A. Mayevsky, "Basic principles of tissue oxygen determination from mitochondrial signals," Oxygen Transport to Tissue. Instrumentation, Methods, and Physiology, H. I. Bicher, D. F. Bruley, Eds., pp. 277-292, Plenum Publishing Corporation, New York (1973).

[3] A. Mayevsky, D. Jamieson, B. Chance, "Oxygen poisoning in unanesthetized brain: Correlation of pyridine nucleotide redox state and electrical activity," Brain Res. 76, 481-491 (1974).

[4] A. Mayevsky, B. Chance, "Repetitive patterns of metabolic changes during cortical spreading depression of the awake rat," Brain Res. 65, 529-533 (1974).

[5] A. Mayevsky, B. Chance, "Metabolic responses of the awake cerebral cortex to anoxia hypoxia spreading depression and epileptiform activity," Brain Res. 98, 149-165 (1975).

[6] A. Mayevsky, B. Chance, "The effect of decapitation on the oxidation-reduction state of NADH and ECoG in the brain of the awake rat," Oxygen Transport to Tissue II, Adv. Exp. Med. Biol., pp. 307-312, Plenum Press, New York (1976).

[7] B. Chance, A. Mayevsky, C. Goodwin, L. Mela, "Factors in oxygen delivery to tissue," Microvasc. Res. 8, 276-282 (1974).

[8] M. Osbakken, A. Mayevsky, I. Ponomarenko, D. Zhang, C. Duska, B. Chance, "Combined in vivo NADH fluorescence and 31P-NMR to evaluate myocardial oxidative phosphorylation," J. Appl. Cardiol. 4, 305-313 (1989).

[9] M. Osbakken, M. Mitchell, D. Zhang, A. Mayevsky, B. Chance, "In vivo correlation of myocardial metabolism, perfusion and mechanical function during increased cardiac work," Cardiovasc. Res. 25, 749-756 (1991).

[10] B. R. Silberstein, A. Mayevsky, B. Chance, "Metabolic responses of the gerbil brain cortex to anoxia, spreading depression, carotid occlusion and stroke," Frontiers in Bioenergetics: From Electrons to Tissues, P. L. Dutton, J. Leigh, A. Scarpa, Eds., pp. 1477-1485, Academic Press, New York (1978).

[11] B. Chance, C. Barlow, Y. Nakase, H. Takeda, A. Mayevsky, R. Fischetti, N. Graham, J. Sorge, "Heterogeneity of oxygen delivery in normoxic and hypoxic states: A fluorometer study," Am. J. Physiol. 235, H809-H820 (1978).

[12] B. Chance, C. Barlow, J. Haselgrove, Y. Nakase, B. Quistorff, F. Matschinsky, A. Mayevsky, "Microheterogeneities of redox states of perfused and intact organs," in Microenvironments and Metabolic Compartmentation, P. Srere, Ed., pp. 221-232, Academic Press, New York (1978).

[13] B. Chance, B. R. Silberstein, A. Mayevsky, "Heterogeneity of metabolic states of the cerebral cortex in vivo," Cerebral Metabolism and Neural Function, J. V. Passoneau, R. A. Hawkins, W. D. Lust, F. A. Welsh, Eds., pp. 77-84, Williams & Wilkins, Baltimore/London (1980).

[14] B. R. Silberstein, A. Mayevsky, B. Chance, "Flying spot studies of brain flavoproteins in the gerbil," Neurol. Res. 2, 19-34 (1980).

[15] A. Mayevsky, H. Kaplan, J. Haveri, J. Haselgrove, B. Chance, "Three-dimensional metabolic mapping of the freeze-trapped brain: Effects of ischemia on the Mongolian gerbil," Brain Res. 367, 63-72 (1986).

[16] J. C. Haselgrove, C. L. Bashford, C. H. Barlow, B. Quistorff, B. Chance, A. Mayevsky, "Time resolved 3-D recording of redox ratio during spreading depression in gerbil brain," Brain Res. 506, 109-114 (1990).

[17] A. Mayevsky, B. Chance, "Intracellular oxidation reduction state measured in situ by a multichannel fiber-optic-surface fluorometer," Science 217, 537-540 (1982).

[18] A. Mayevsky, B. Chance, "Multisite measurements of NADH redox state from cerebral cortex of the awake animal," Oxygen Transport to Tissue, IV, H. I. Bicher and D. F. Bruley, Eds., pp. 143-155, Plenum Publishing Corporation, New York (1983).

[19] A.Mayevsky, T. Zeuthen, B. Chance, "Measurements of extracellular potassium, ECoG and pyridine nucleotide levels during cortical spreading depression in rats," Brain Res. 76, 347-349 (1974).

[20] A. Mayevsky, S. Lebourdais, B. Chance, "The interrelation between brain PO2 and NADH oxidation-reduction state in the gerbil," J. Neurosci. Res. 5, 173-182 (1980).

[21] A. Mayevsky, K. H. Frank, S. Nioka, M. Kessler, B. Chance, "Oxygen supply and brain function in vivo: A multiparametric monitoring approach in the Mongolian gerbil," Oxygen Transport to Tissue XII, J. Piiper, T. K. Goldstick, M. Meyer, Eds., pp. 303-313, Plenum Press, New York (1990).

[22] A. Mayevsky, K. Frank, M. Muck, S. Nioka, M. Kessler, B. Chance, "Multiparametric evaluation of brain functions in the Mongolian gerbil in vivo," J. Basic Clin. Physiol. Pharmacol. 3, 323-342 (1992).

[23] A. Mayevsky, V. H. Subramanian, S. Nioka, C. Barlow, J. Haselgrove, B. Chance, "Brain energy metabolism evaluated simultaneously in the newborn dog by 31P-NMR spectroscopy and NADH fluorometry/reflectometry in vivo," J. CBF Metab. Suppl., pp. 400-401 (1985).

[24] A. Mayevsky, S. Nioka, V. H. Subramanian, B. Chance, "Microcirculatory responses to brain hypoxia in the newborn dog as evaluated by P-NMR spectroscopy and NADH fluorometry/reflectometry in vivo," Microcirculation — An Upadate, M. Tsuchiya, M. Asano, Y. Mishima, M. Oda, Eds., pp. 49-50, Excerpta Medica, Amsterdam (1987).

[25] A. Mayevsky, S. Nioka, B. Chance, "Fiber optic surface fluorometry/reflectometry and 31P-NMR for monitoring the intracellular energy state in vivo," Oxygen Transport to Tissue X, M. Mochizuki, C. R. Honig, T. Koyama, T. K. Goldstick, D. F. Bruley, Eds., pp. 365-374, Plenum Press, New York (1988).

[26] A. Mayevsky, S. Nioka, V. H. Subramanian, B. Chance, "Brain oxidative metabolism of the newborn dog: Correlation between 31P-NMR spectroscopy and pyridine nucleotides redox state," J. CBF Metab. 8, 201-207 (1988).

[27] A. Mayevsky, S. Nioka, D. J. Wang, B. Chance, "The functioning gerbil brain in vivo: Correlation between 31P-NMR spectroscopy and the multiparametric monitoring approach," Oxygen Transport to Tissue XVIII, E. M. Nemoto, J. C. LaManna, Eds., pp. 41-53, Plenum Press, New York (1997).

[28] A. Mayevsky, E. S. Flamm, W. Pennie, B. Chance, "A fiber-optic-based multiprobe system for intraoperative monitoring of brain functions," SPIE Proc. 1431, 303-313 (1991).

[29] A. Mayevsky, B. Chance, "Oxidation-reduction states of NADH in vivo: From animals to clinical use," Mitochondrion 7, 330-339 (2007).

[30] M. Maris, A. Mayevsky, B. Chance, "Frequency domain dynamic measurements of changes of optical pathlength during spreading depression in rodent brain mode," SPIE Proc. 1431, 136-148 (1991).

[31] B. Chance, A. Mayevsky, B. Guan, Y. Zhang, "Hypoxia/ischemia triggers a light scattering event in rat brain," Adv. Exp. Med. Biol. 428, 457-467 (1997).

[32] S. Nioka, B. Chance, D. S. Smith, A. Mayevsky, M. P. Reilly, C. Alter, T. Asakura, "Cerebral energy metabolism and oxygen state during hypoxia in neonate and adult dogs," Pediatr. Res. 28, 54-62 (1990).

[33] S. Nioka, D. S. Smith, A. Mayevsky, G. Dobson, R. L. Veech, H. Subramanian, B. Chance, "Age dependence of steady state mitochondrial oxidative metabolism in the in vivo g hypoxic dog brain," Neurol. Res. 13, 25-32 (1991).

[34] A. Mayevsky, G. G. Rogatsky, "Mitochondrial function in vivo evaluated by NADH fluorescence: From animal models to human studies," Am. J. Physiol. Cell. Physiol. 292, C615-C640 (2007).

[35] A. Mayevsky, "Brain energy metabolism of the conscious rat exposed to various physiological and pathological situations," Brain Res. 113, 327-338 (1976).

[36] B. Chance, V. Legallias, B. Schoener, "Combined fluorometer and double-beam spectrophotometer for reflectance measurements," Rev. Sci. Instrum. 34, 1307-1311 (1963).

[37] F. F. J€obsis, W. N. Stainsby, "Oxidation of NADH during contractions of circulated mammalian skeletal muscle," Respir. Physiol. 4, 292-300 (1968).

[38] A. Mayevsky, C. M. Friedli, M. Reivich, "Metabolic, ionic and electrical responses of the gerbil brain to ischemia," Am. J. Physiol. 248, R99-R107 (1985).

[39] A. Mayevsky, U. Marchaim, "Studies on the effect of Iucerne saponines on the respiration of cottonseeds using 18O2," Plant Cell Physiol. 13, 927-930 (1972).

[40] A. Mayevsky, D. Samuel, S. S. Friedland, J. H. Ewins, "In vivo measurement of 32P in the brain of a freely moving rat," J. Neurosci. Res. 1, 275-286 (1975).

[41] J. Sonn, A. Mayevsky, "The effect of ethanol on metabolic, hemodynamic and electrical responses to cortical spreading depression," Brain Res. 908, 174-186 (2001).

[42] K. C. Wadhwani, S. I. Rapoport, "Blood flow in the central and peripheral nervous systems," Laser Doppler Blood Flowmetry, A. P. Shephard and P. A. Oberg, Eds., pp. 265-304, Kluwer Academic Pub., Boston (1990).

[43] B. Chance, P. Cohen, F. J€obsis, B. Schoener, "Intracellular oxidation-reduction states in vivo," Science 137, 499-508 (1962).

[44] A. Mayevsky, "Brain NADH redox state monitored in vivo by fiber optic surface fluorometry," Brain Res. Rev. 7, 49-68 (1984).

[45] W. Crowe, A. Mayevsky, L. Mela, "Application of a solid membrane ion selective electrode to in vivo measurements," Am. J. Physiol. 233, C56-C60 (1977).

[46] E. Yoles, N. Zarchin, A. Mayevsky, "Effects of age on the metabolic ionic and electrical responses to anoxia in the newborn dog brain in vivo," J. Basic Clin. Physiol. Pharmacol. 2, 297-313 (1991).

[47] A. Mayevsky, Y. Blum, N. Dekel, A. Deutsch, R. Halfon, S. Kremer, E. Pewzner, E. Sherman, O. Barnea, "The CritiView — A new fiber-opticbased optical device for the assessment of tissue vitality," Proc. SPIE 6083, 60830Z-1-60830Z-9 (2006).

[48] A. Harden, W. Young, "The alcoholic ferment of yeast-juice," Proc. Roy. Soc. 77, 405-120 (1906).

[49] O. Warburg, W. Christian, A. Griese, "Hydrogen transferring coenzyme; its composition and mode of action," J. Biochem. 282, 157-205 (1935).

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[51] H. Theorell, R. Bonnichsen, "Studies on liver alcohol dehydrogenase. I. Equilibria and initial reaction velocities," Acta Chem. Scand. 5, 1105-1126 (1951).

[52] B. Chance, V. Legallias, "Rapid and sensitive spectrophotometry. A stopped-flow attachment for a stabilized quartz spectrophotometer," Rev. Sci. Instrum. 22, 627-638 (1951).

[53] B. Chance, J. B. Neilands, "Studies on lactic dehydrogenase of heart. II. A compound of lactic dehydrogenase and reduced pyridine nucleotide," J. Biol. Chem. 199, 383-387 (1952).

[54] B. Chance, "Spectrophotometry of intracellular respiratory pigments," Science 120, 767-775 (1954).

[55] B. Chance, G. R. Williams, "Respiratory enzymes in oxidative phosphorylation. III. The steady state," J. Biol. Chem. 217, 409-427 (1955).

[56] L. N. M. Duysens, J. Amesz, "Fluorescence spectrophotometry of reduced phosphopyridine nucleotide in intact cells in the near-ultraviolet and visible region," Biochim. Biophys. Acta 24, 19-26 (1957).

[57] B. Chance, H. Baltscheffsky, "Respiratory enzymes in oxidative phosphorylation," J. Biol. Chem. 233, 736-739 (1958).

[58] B. Chance, F. J€obsis, "Changes in fluorescence in a frog sartorius muscle following a twitch," Nature 184, 195-196 (1959).

[59] B. Chance,V. Legallias, B. Schoener, "Metabolicallylinked changes in fluorescence emission spectra of cortex of rat brain, kidney and adrenal gland," Nature 195, 1073-1075 (1962).

[60] B. Chance, D. Jamieson, H. Coles, "Energy-linked pyridine nucleotide reduction: Inhibitory effects of hyperbaric oxygen in vitro and in vivo," Nature 206, 257-263 (1965).

[61] F. F. J€obsis, M. O'Connor, A. Vitale, H. Vreman, "Intracellular redox changes in functioning cerebral cortex. I. Metabolic effects of epileptiform activity," Neurophysiology 34, 735-749 (1971).

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[63] A. Mayevsky, A. Doron, T. Manor, S. Meilin, N. Zarchin, G. E. Ouaknine, "Cortical spreading depression recorded from the human brain using a multiparametric monitoring system," Brain Res. 740, 268-274 (1996).

[64] A. Mayevsky, T. Manor, E. Pewzner, A. Deutsch, R. Etziony, N. Dekel, "Real time optical monitoring of tissue vitality in vivo," SPIE 4616, 30-39 (2002).