• Journal of Innovative Optical Health Sciences
  • Vol. 3, Issue 3, 177 (2010)
RAN LIAO1, NAN ZENG1, DONGZHI LI1、2, TIANLIANG YUN1、2, YONGHONG HE1, and HUI MA1、2、*
Author Affiliations
  • 1Laboratory of Optical Imaging and Sensing Graduate School at Shenzhen, Tsinghua University Shenzhen 518055, China
  • 2Key Laboratory for Molecular and Nanosciences of Education Ministry Department of Physics, Tsinghua University Beijing 100084, China
  • show less
    DOI: 10.1142/s1793545810000988 Cite this Article
    RAN LIAO, NAN ZENG, DONGZHI LI, TIANLIANG YUN, YONGHONG HE, HUI MA. A STUDY ON PENETRATION DEPTH OF POLARIZATION IMAGING[J]. Journal of Innovative Optical Health Sciences, 2010, 3(3): 177 Copy Citation Text show less

    Abstract

    Optical clearing improves the penetration depth of optical measurements in turbid tissues. Polarization imaging has been demonstrated as a potentially promising tool for detecting cancers in superficial tissues, but its limited depth of detection is a major obstacle to the effective application in clinical diagnosis. In the present paper, detection depths of two polarization imaging methods, i.e., rotating linear polarization imaging (RLPI) and degree of polarization imaging (DOPI), are examined quantitatively using both experiments and Monte Carlo simulations. The results show that the contrast curves of RLPI and DOPI are different. The characteristic depth of DOPI scales with transport mean free path length, and that of RLPI increases slightly with g. Both characteristic depths of RLPI and DOPI are on the order of transport mean free path length and the former is almost twice as large as the latter. It is expected that they should have different response to optical clearing process in tissues.
    RAN LIAO, NAN ZENG, DONGZHI LI, TIANLIANG YUN, YONGHONG HE, HUI MA. A STUDY ON PENETRATION DEPTH OF POLARIZATION IMAGING[J]. Journal of Innovative Optical Health Sciences, 2010, 3(3): 177
    Download Citation