Several problems on the flight control system design of Near Space Vehicle (NSV) are discussed.Firstly,the recent developments and the importance of NSV research are introduced.Then,several important problems for the NSV flight control are discussed,including:1) modeling of NSV flight motion control;2) robustness of NSV flight attitude control；3) integrated coordination control between flight attitude and centre-of-gravity motion;4) integrated coordination control between flight and engine control;and 5) anti-disturbance of flight control.The corresponding view is given and methods are proposed for solution of the problems.At last,the authors viewpoints on design principles of NSV flight control system are presented,and the significance of applying integrated coordination control idea in NSV flight control system design is pointed out.Key words：讨论了近空间飞行器飞行控制系统研究设计的几个问题。首先指出了研究近空间飞行器的国内外形势和近空间飞行器研究的重要性;接着就近空间飞行器飞行控制的几个重要问题：飞行运动控制的建模问题，飞行姿态控制的鲁棒性问题，飞行姿态与重心运动的一体化协调控制问题，飞行与发动机的一体化协调控制问题，飞行控制的抗干扰问题提出了相应的方法和看法;最后就近空间飞行器飞行控制系统的设计原则提出了自己的体会和看法，指出了用一体化协调控制的思想进行近空间飞行器飞行控制系统分析设计的重要性。