There are many kinds of suspended particles in natural environment, and research on scattering characteristics of particles has extensive application value. The existing theoretical calculation is complex, and it is often based on assuming a homogeneous composition sphere model without the difference of particle’s internal composition structure. Through the analysis of calculation for extinction and absorption efficiency of two- layered homogeneous sphere model, the anomalous diffraction approximation method is extended to multilayered homogeneous particle model. The corresponding error comparison illustrates the usefulness of the method. The scattering properties of two- layered homogeneous particles with different internal and external sphere parameters and offcenter deviations are discussed by taking marine plankton as an example.The simulation results show that except for size and refractive index, particle heterogeneous structure also plays a role on the forward scattering. When the difference between inner and outer sphere parameters is large, it is necessary to consider the influence of structural factors on the scattering properties.