Simulation of transport properties in mid-infrared quantum cascade lasers (QCLs) with different structures at different temperatures based on non-local transport model is reported. With this model, drift-diffusion equations were solved with modification of current density by accounting for long-range carrier transport including quantum tunneling, mini-band tunneling and hot carrier transport in the device. The simulation with the above model was compared with experimental data and reasonable agreements with experiments have been obtained with some reasonable fitting parameters.