[1] J. Ferlay, I. Soerjomataram, R. Dikshit, S. Eser, C. Mathers, M. Rebelo et al., "Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012," Int. J. Cancer 136, E359–E386 (2015).

[2] Z. U. Khan, "An overview of oral cancer in Indian subcontinent and recommendations to decrease its incidence," WebmedCentralCANCER3(8), WMC003626 (2012).

[3] R. Sankaranarayanan, K. Ramadas, G. Thomas, R. Muwonge, S. Thara, B. Mathew et al., "Effect of screening on oral cancer mortality in Kerala, India: A cluster-randomised controlled trial," Lancet 365, 1927–1933 (2005).

[4] M. Hashibe, P. Brennan, S. Benhamou, X. Castellsague, C. Chen, M. P. Curado et al., "Alcohol drinking in never users of tobacco, cigarette smoking in never drinkers, and the risk of head and neck cancer: Pooled analysis in the International Head and Neck Cancer Epidemiology Consortium," J. Nat. Cancer Inst. 99, 777–789 (2007).

[5] S. Khandekar, P. Bagdey, R. Tiwari, "Oral cancer and some epidemiological factors: A hospital based study," Indian J. Commun. Med. 31, 157–159 (2006).

[6] S. Kumar, R. Heller, U. Pandey, V. Tewari, N. Bala, K. Oanh, "Delay in presentation of oral cancer: A multifactor analytical study," Nat. Med. J. India 14, 13–17 (2001).

[7] R. E. Pollock, J. H. Doroshow, UICC Manual of Clinical Oncology, Wiley-liss, New York (2004).

[8] S. Carnelio, G. Rodrigues, "Oral cancer at a glance," Internet J. Dent. Sci. 1, 1–12 (2004).

[9] S. Warnakulasuriya, "Global epidemiology of oral and oropharyngeal cancer," Oral Oncol. 45, 309– 316 (2009).

[10] S. S. Napier, P. M. Speight, "Natural history of potentially malignant oral lesions and conditions: An overview of the literature," J. Oral Pathol. Med. 37, 1–10 (2008).

[11] I. van der Waal, "Potentially malignant disorders of the oral and oropharyngeal mucosa; present concepts of management," Oral Oncol. 46, 423–425 (2010).

[12] C. F. Poh, S. Ng, K. W. Berean, P. M. Williams, M. P. Rosin, L. Zhang, "Biopsy and histopathologic diagnosis of oral premalignant and malignant lesions," J. Canad. Dent. Assoc. 74, 283–288 (2008).

[13] A. Karabulut, J. Reibel, M. H. Therkildsen, F. Pr torius, H. Nielsen, E. Dabelsteen, "Observer variability in the histologic assessment of oral premalignant lesions," J. Oral Pathol. Med. 24, 198–200 (1995).

[14] D. V. Messadi, "Diagnostic aids for detection of oral precancerous conditions," Int. J. Oral Sci. 5, 59–65 (2013).

[15] M. DeCoro, P. Wilder-Smith, "Potential of optical coherence tomography for early diagnosis of oral malignancies," Expert Review of Anticancer Therapy 10(3), 321–329 (2010).

[16] T. J. Muldoon, D. Roblyer, M. D. Williams, V. M. Stepanek, R. Richards-Kortum, A. M. Gillenwater, "Noninvasive imaging of oral neoplasia with a highresolution fiber-optic microendoscope," Head Neck 34, 305–312 (2012).

[17] A. Sharwani, W. Jerjes, V. Salih, B. Swinson, I. Bigio, M. El-Maaytah et al., "Assessment of oral premalignancy using elastic scattering spectroscopy," Oral Oncol. 42, 343–349 (2006).

[18] P. Chaturvedi, S. K. Majumder, H. Krishna, S. Muttagi, P. K. Gupta, "Fluorescence spectroscopy for noninvasive early diagnosis of oral mucosal malignant and potentially malignant lesions," J. Cancer Res. Therapeut. 6, 497 (2010).

[19] R. Malini, K. Venkatakrishna, J. Kurien, K. M Pai, L. Rao, V. Kartha et al., "Discrimination of normal, inflammatory, premalignant, and malignant oral tissue: A Raman spectroscopy study," Biopolymers 81, 179–193 (2006).

[20] S. Singh, A. Deshmukh, P. Chaturvedi et al., "In vivo Raman spectroscopy for oral cancers diagnosis," SPIE BiOS, Vol. 8219, International Society for Optics and Photonics, 2012, p. 82190K-82190K- 82196.

[21] S. Singh, A. Deshmukh, P. Chaturvedi, C. M. Krishna, "In vivo Raman spectroscopic identification of premalignant lesions in oral buccal mucosa," J. Biomed. Opt. 17, 1050021–1050029 (2012).

[22] S. N. Shaiju, S. Ariya, R. Asish, P. S. Haris, B. Anita, G. A. Kumar et al., "Habits with killer instincts: In vivo analysis on the severity of oral mucosal alterations using autofluorescence spectroscopy," J. Biomed. Opt. 16, 087006-087006-13 (2011).

[23] A. Gillenwater, R. Jacob, R. Ganeshappa, B. Kemp, A. K. El-Naggar, J. L. Palmer et al., "Noninvasive diagnosis of oral neoplasia based on fluorescence spectroscopy and native tissue autofluorescence," Arch. Otolaryngol.–Head Neck Surg. 124, 1251–1258 (1998).

[24] C.-K. Lee, T.-T. Chi, C.-T. Wu, M.-T. Tsai, C.-P. Chiang, C.-C. C. Yang, "Diagnosis of oral precancer with optical coherence tomography," Biomed. Opt. Express 3, 1632–1646 (2012).

[25] S. Singh, A. Sahu, A. Deshmukh, P. Chaturvedi, C. M. Krishna, "In vivo Raman spectroscopy of oral buccal mucosa: A study on malignancy associated changes (MAC)/cancer field effects (CFE)," Analyst 138, 4175–4182 (2013).

[26] A. Sahu, A. Deshmukh, A. Ghanate, S. Singh, P. Chaturvedi, C. M. Krishna, "Raman spectroscopy of oral buccal mucosa: A study on age-related physiological changes and tobacco-related pathological changes," Technol. Cancer Res. Treat. 11, 529–541 (2012).

[27] E. M. Barroso, R. W. H. Smits, T. Bakker Schut, I. ten Hove, J. A. Hardillo, E. B. Wolvius et al., "Discrimination between oral cancer and healthy tissue based on water content determined by Raman spectroscopy," Anal. Chem. 87, 2419–2426 (2015).

[28] F. L. Cals, T. C. B. Schut, J. A. Hardillo, R. J. B. de Jong, S. Koljenovi , G. J. Puppels, "Investigation of the potential of Raman spectroscopy for oral cancer detection in surgical margins," Lab. Invest. 95(10), 1186–1196 (2015).

[29] R. Z. German, J. B. Palmer, "Anatomy and development of oral cavity and pharynx," GI Motility Online (2006).

[30] T. A. Winning, G. C. Townsend, "Oral mucosal embryology and histology," Clin. Dermatol. 18, 499–511 (2000).

[31] D.C. deVeld, M. Skurichina,M. J.Witjes, R.P. Duin, D. J. Sterenborg, W. M. Star et al., "Autofluorescence characteristics of healthy oral mucosa at different anatomical sites," Lasers Surg. Med. 32, 367–376 (2003).

[32] S. McGee, V. Mardirossian, A. Elackattu, J. Mirkovic, R. Pistey, G. Gallagher et al., "Anatomybased algorithms for detecting oral cancer using re- flectance and fluorescence spectroscopy," Ann. Otol. Rhinol. Laryngol. 119, 817–826 (2010).

[33] S. McGee, J. Mirkovic,V.Mardirossian, A. Elackattu, C.-C. Yu, S. Kabani et al., "Model-based spectroscopic analysis of the oral cavity: Impact of anatomy," J. Biomed. Opt. 13, 064034-064034-15 (2008).

[34] K. Guze, M. Short, S. Sonis, N. Karimbux, J. Chan, H. Zeng, "Parameters defining the potential applicability of Raman spectroscopy as a diagnostic tool for oral disease," J. Biomed. Opt. 14, 014016-014016- 9 (2009).

[35] M. S. Bergholt, W. Zheng, Z. Huang, "Characterizing variability in in vivo Raman spectroscopic properties of different anatomical sites of normal tissue in the oral cavity," J. Raman Spectrosc. 43, 255–262 (2012).

[36] H. Krishna, S. K. Majumder, P. Chaturvedi, P. K. Gupta, "Anatomical variability of in vivo Raman spectra of normal oral cavity and its effect on oral tissue classification," Biomed. Spectrosc. Imag. 2, 199–217 (2013).

[37] H. Krishna, S. K. Majumder, P. Chaturvedi, M. Sidramesh, P. K. Gupta, "In vivo Raman spectroscopy for detection of oral neoplasia: A pilot clinical study," J. Biophoton. 7, 690–702 (2014).

[38] A. Nijssen, K. Maquelin, L. F. Santos, P. J. Caspers, T. C. B. Schut, J. C. den Hollander et al., "Discriminating basal cell carcinoma from perilesional skin using high wave-number Raman spectroscopy," J. Biomed. Opt. 12, 034004-034004-7 (2007).

[39] S. Koljenovi , T. C. B. Schut, J. M. Kros, H. J. van den Berge, G. J. Puppels, "Discriminating vital tumor from necrotic tissue in human glioblastoma tissue samples by Raman spectroscopy," Lab. Invest. 82, 1265–1277 (2002).

[40] P. Crow, B. Barrass, C. Kendall, M. Hart-Prieto, M. Wright, R. Persad et al., "The use of Raman spectroscopy to differentiate between different prostatic adenocarcinoma cell lines," Br. J. Cancer 92, 2166– 2170 (2005).

[41] T. Harvey, E. Gazi, A. Henderson, R. Snook, N. Clarke, M. Brown et al., "Factors influencing the discrimination and classification of prostate cancer cell lines by FTIR microspectroscopy," Analyst 134, 1083–1091 (2009).

[42] T. C. Bakker Schut, R. Wolthuis, P. J. Caspers, G. J. Puppels, "Real-time tissue characterization on the basis of in vivo Raman spectra," J. Raman Spectrosc. 33, 580–585 (2002).

[43] J. G. Kelly, J. Trevisan, A. D. Scott, P. L. Carmichael, H. M. Pollock, P. L. Martin-Hirsch et al., "Biospectroscopy to metabolically profile biomolecular structure: A multistage approach linking computational analysis with biomarkers," J. Proteome Res. 10, 1437–1448 (2011).

[44] A. Ghanate, S. Kothiwale, S. Singh, D. Bertrand, C. M. Krishna, "Comparative evaluation of spectroscopic models using different multivariate statistical tools in a multicancer scenario," J. Biomed. Opt. 16, 025003-025003-9 (2011).

[45] F. S. Parker, Applications of Infrared, Raman, and Resonance Raman Spectroscopy in Biochemistry, Springer Science & Business Media, New York and London (1983).

[46] Z. Movasaghi, S. Rehman, I. U. Rehman, "Raman spectroscopy of biological tissues," Appl. Spectrosc. Rev. 42, 493–541 (2007).

[47] K. Guze, H. C. Pawluk, M. Short, H. Zeng, J. Lorch, C. Norris et al., "Pilot study: Raman spectroscopy in differentiating premalignant and malignant oral lesions from normal mucosa and benign lesions in humans," Head Neck 37, 511–517 (2015).

[48] K. M. Baldwin, Wheater Review of Histology and Basic Pathology, Churchill Livingstone (2010).

[49] G. Kumar, Orban's Oral Histology & Embryology, Elsevier Health Sciences, New York (2014).

[50] A. Nanci, Ten Cate's Oral Histology-Pageburst on VitalSource: Development, Structure, and Function, Elsevier Health Sciences, New York (2007).

[51] C. Squier, M. Finkelstein, "Oral mucosa," Ten Cate's Oral Histology: Development, Structure, and Function, 6th Edition. Mosby, St. Louis (2003), pp. 369–372.