Overview: With the rapid development of aerospace, energy power, petrochemical, and other fields, nickel-based alloy sheet welding technology has become one of the key factors determining the performance of core components. The welding of nickel base alloy sheet is sensitive to the heat input, and it is easy to cause element segregation and brittle phase precipitation, which will reduce the weld performance and produce welding deformation. This paper introduces the research progress of laser welding technology of nickel base alloy sheet, and summarizes the evolution of weld microstructure, changes of mechanical properties and corrosion resistance, and the rules of welding deformation under two kinds of welding technologies including laser autogenous welding and laser welding with filler wire of nickel base alloy sheet. The research of the autogenous laser welding process focuses on Ni-Cr and Ni-Cr-Mo alloys. The grain morphology and element segregation are analyzed, including refining microstructure and inhibiting the formation of precipitates, by means of adjusting the process parameters, using ultrasonic vibration, and using a low-temperature cooling process. The microhardness of the two kinds of alloy welds is better than that of base metal, because of the finer grains in the welds. Tensile strength at room temperature can reach about 90% of the base metal, but high-temperature tensile performance is comparable to the base metal. Ni-Cr alloy welded joints show good high-temperature plasticity. The relatively lower tensile strength of the welded joints is relative to the worse morphology of the weld surfaces. The fatigue properties and corrosion resistance of the Ni-Cr-Mo alloy welds are comparable to those of the base metal. The research of laser welding of nickel-based alloy sheets with filler wire focuses on the Ni-Cr-Mo alloy, and the grain morphology, element segregation, and its regulation are still the focuses of the research. The microhardness and room temperature tensile strength of the welded joints with filler wire are better than those of the base metal. The better room temperature tensile strength of the welded joints benefits from both the finer weld grains and the occurrence of the reinforcement. Corrosion tests show that the welded joints have comparable corrosion resistance to the base metal. Welding deformation of nickel-based alloy sheets includes shrinkage deformation, deflection, and angular deformation. Compare with the traditional arc welding process, laser welding shows lower heat input, and thus, it leads to smaller deformation. At present, the research of welding deformation of nickel-based alloy sheet mainly concentrates on the prediction of deformation through the finite element method and reducing deformation through process parameters adjustment, restraint intensity control, and utilizing auxiliary processes. Future research should focus on the prediction of weld microstructure and the propose of various adaptive control strategies for microstructure, mechanical properties and corrosion resistance by combining with advanced algorithms. Besides, developing new types of intelligent welding processes is also an important part.With the rapid development of aerospace, energy power, petrochemical, and other fields, nickel-based alloy sheet welding technology has become one of the key factors determining the performance of core components. The welding of nickel base alloy sheet is sensitive to the heat input, and it is easy to cause element segregation and brittle phase precipitation, which will reduce the weld performance and produce welding deformation. This paper introduces the research progress of laser welding technology of nickel base alloy sheet, and summarizes the evolution of weld microstructure, changes of mechanical properties and corrosion resistance, and the rules of welding deformation under two kinds of welding technologies including laser autogenous welding and laser welding with filler wire of nickel base alloy sheet. It is proposed that the prediction of weld microstructure should be considered in the future research, which should combine with advanced algorithms to propose the adaptive control strategy of microstructure, mechanical properties and corrosion resistance, developing a new intelligent welding process.