A three-dimensional TC17 thick-walled part was formed on a TA0 substrate using point-mode forging laser deposition technology. Its deposited and annealed structure and mechanical properties were analyzed using an optical microscope, scanning electron microscope, uniaxial tensile test, and microhardness test. The results show that the original macroscopic grains have an equiaxed morphology, and the grains' interiors are formed by numerous primary fine α laths, few equiaxed α phases, and β transformation structures. The uniaxial tensile test was performed at room temperature along the deposition height direction and vertical deposition height direction. Tensile strength in both directions exceeded the national standard for forgings in the annealed state. The hardness test shows that the original deposition area has a Vickers hardness of ~400 HV, and the hardness exhibits a downward trend as the temperature increases. The uniaxial tensile test results show that the strength and plasticity in both directions significantly reduced after annealing at 850 ℃/1 h. After annealing at 610 ℃/1 h, the material's strength is significantly increased, and the plasticity is significantly reduced. After annealing at 730 ℃/1 h, the sample's strength in both directions is slightly reduced compared with the deposited state, but its plasticity is improved. The scanning electron microscope photos show that the tensile fracture dimples formed after 730 ℃ treatment are deep and dense, indicating toughness fracture.