In order to simplify the thighbone tumor surgery and improve the accuracy of the areas to be cut, a kind of surgery orienting model for the surgery operation is designed according to the scanning data of computer tomography (CT) and the three-dimensional reconstruction image. By using the Dimetal-280 selective laser melting rapid prototyping system, the surgery orienting model of 316 L stainless steel is made through orthogonal experiment for processing parameter optimization. The technology of direct manufacturing of surgery orienting model by selective laser melting(SLM) shows obvious superiority with high speed, precise profile and good accuracy in size comparing with the traditional ones. The model has been well applied in a real surgery operation for thighbone replacement operation. The successful development of the model provides a new method for the automatic manufacture of customized implants and surgery model, and will build a foundation for more clinical applications in the future.