The infrared focal plane arrays (IRFPAs) technology has been driven to the third generation. Readout integrated circuit (ROIC) is an important subassembly of focal plane arrays. To reach the ideal working state, ROIC needs to be supplied with clock drive impulse and setup voltage. IRFPAs driving circuit using atme189s51 singlechip has been designed, which has facility performance, powerful drive ability. While the out-put voltages are high and low, the output driving currents are 4 mA and 28 mA separately. It can be used to drive 128×1 IRFPAs. Via brief modification in program, driving circuit can adjust clock drive impulse frequency、integration time and readout time etc, which can be used to drive 256×1 IRFPAs.