Low-loss and flexible hollow optical fibers were fabricated based on the polycarbonate capillary. Silver and cyclic olefin polymer films were innerly coated to enhance the reflectance at objective wavelengths. By optimizing the liquid-phase coating parameters, polymer layer obtained optimum thickness for simultaneous transmission for Er∶YAG and visible pilot beams. Polycarbonate capillary based hollow fibers are flexible and safe, which makes it possible to deliver infrared laser power in endoscopic application. The transmission losses are 0.4 dB/m and 3 dB/m for the 2.94 μm Er∶YAG laser and red visible laser, respectively. The transmittance of Er∶YAG laser light is about 70% and loss of visible pilot beam is 11 dB when the fiber was sharply bent with a bending radius as small as 0.9 centimeter and bending angle at 135°. Experimental results show that cyclic olefin polymer coated silver hollow polycarbonate fiber are suitable for the delivery of endoscopic laser and visible pilot beam.