Ultraviolet laser-induced ferroelectric domain inversion in nearly-stoichiometric LiTaO3 was investigated. The continuous ultraviolet laser with 351 nm wavelength was focused on the -z surface of nearly-stoichiometric LiTaO3, and the homogeneous electric field which was antiparallel to the direction of spontaneous polarization was applied simultaneously. It is proved that the coercive field is effectively reduced by the laser radiation. The local domain inversion induced in the laser radiation area is confirmed by the digital holographic interferometry. The investigation proves that the ferroelectric domain inversion can be locally controlled by the ultraviolet laser irradiation. It is regarded that the defect structure with jumbo size and high density in the crystal lattice is generated by the complex coaction of incident irradiation field and external electric field. The defect dominates the nucleation by reducing depolarization energy and domain-wall energy required for domain-nucleus growth and domain wall movement, and the laser-induced domain inversion is realized.