Author Affiliations
1Beijing Key Laboratory of Computational Intelligence and Intelligent System, Faculty of Information Technology, Beijing University of Technology, Beijing 100124, China2Beijing Laboratory of Advanced Information Networks, Beijing 100124, Chinashow less
Fig. 1. Diagram of CELSI
[3]. (a) CELSI imaging instrument; (b) process of photon excitation
Fig. 2. Structure of completely bipartite factor graph
Fig. 3. Flow chart of AMP algorithm
Fig. 4. Phantom used in experiments
Fig. 5. Reconstructed images obtained by different algorithms with varied contrasts. Contrast of Figs. 5(a)--(f) is reduced from 4 to 1.5 by step of 0.5
Fig. 6. Profiles along horizontal line of reconstructed images of single target. (a) Contrast is 4; (b) contrast is 3; (c) contrast is 2
Fig. 7. Distributions of true single targets with different radii and reconstruction results obtained by different algorithms. (a)--(e) Radius of fluorescent target decreases from 7 mm to 3 mm with a step of 1 mm
Fig. 8. Comparison of results obtained by different reconstruction methods for single targets with varied radius. (a) CNR; (b) MSE
Fig. 9. Reconstruction results of different algorithms for multiple fluorescent targets
Opticalparameter | μax | μam | μ'sx | μ'sm | ημaf |
---|
Value | 0.009 | 0.006 | 1.31 | 1.27 | 2.0×10-4 |
|
Table 1. Background optical parameters of phantommm-1
Contrast | CNR | MSE | PSNR | FWHM |
---|
Tikhonov | ISTA | AMP | Tikhonov | ISTA | AMP | Tikhonov | ISTA | AMP | Tikhonov | ISTA | AMP |
---|
4 | 9.57 | 12.30 | 13.89 | 4.68×10-4 | 4.06×10-4 | 3.71×10-4 | 21.86 | 24.24 | 25.61 | 16.16 | 16.16 | 14.14 | 3.5 | 9.09 | 11.91 | 13.53 | 3.99×10-4 | 3.45×10-4 | 3.15×10-4 | 22.49 | 24.41 | 25.82 | 20.20 | 16.16 | 14.14 | 3 | 8.58 | 11.51 | 13.13 | 3.28×10-4 | 2.82×10-4 | 2.57×10-4 | 23.39 | 24.80 | 26.21 | 20.20 | 18.18 | 16.16 | 2.5 | 8.12 | 11.06 | 12.65 | 2.52×10-4 | 2.16×10-4 | 1.97×10-4 | 23.64 | 25.54 | 26.91 | 23.23 | 20.20 | 17.17 | 2 | 6.71 | 10.55 | 12.11 | 1.83×10-4 | 1.48×10-4 | 1.35×10-4 | 24.63 | 27.05 | 28.33 | 31.31 | 24.24 | 20.20 | 1.5 | 5.21 | 9.96 | 11.38 | 1.08×10-4 | 0.76×10-4 | 0.70×10-4 | 27.77 | 30.79 | 31.79 | 67.68 | 48.48 | 40.40 |
|
Table 2. Quantitative comparison of reconstruction results obtained by three different methods (Tikhonov, ISTA, and AMP) with varied contrast
Method | Reconstruction time |
---|
Contrast is 4 | Contrast is 3.5 | Contrast is 3 | Contrast is 2.5 | Contrast is 2 | Contrast is 1.5 |
---|
Tikhonov | 48 | 49 | 48 | 48 | 40 | 39 | ISTA | 110 | 110 | 110 | 112 | 114 | 109 | AMP | 101 | 102 | 103 | 102 | 100 | 104 |
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Table 3. Reconstruction time for different algorithms with varied contrasts
Method | Two targets | Three targets |
---|
CNR | MSE | CNR | MSE |
---|
T1 | T2 | T1 | T2 | T1 | T2 | T3 | T1 | T2 | T3 | Tikhonov | 7.23 | 7.23 | 2.85×10-4 | 2.84×10-4 | 9.46 | 7.40 | 5.40 | 1.44×10-4 | 2.69×10-4 | 3.21×10-4 | GPSR | 4.30 | 4.52 | 4.58×10-4 | 4.51×10-4 | 9.47 | 3.37 | 2.37 | 2.08×10-4 | 4.55×10-4 | 4.40×10-4 | TwIST | 1.71 | 4.06 | 4.71×10-4 | 4.70×10-4 | 5.53 | 1.34 | 0.65 | 4.56×10-4 | 5.52×10-4 | 5.06×10-4 | ISTA | 8.70 | 8.57 | 2.57×10-4 | 2.61×10-4 | 9.84 | 6.88 | 4.98 | 1.48×10-4 | 3.03×10-4 | 3.43×10-4 | AMP | 10.14 | 10.09 | 2.19×10-4 | 2.18×10-4 | 9.86 | 8.10 | 6.20 | 1.34×10-4 | 2.43×10-4 | 2.74×10-4 |
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Table 4. Quantitative reconstruction results obtained by different algorithms for multiple fluorescent targets