Multispectral imaging technology is the key for high-fidelity reproduction of objects in various environments. In computer graphics, the rendering method based on multispectral has obvious advantages compared with those of the traditional three-channel red-green-blue (RGB) color rendering method because of the explicit physical meaning of imaging. The basic principle of multispectral imaging is discussed, and the necessary approximation in implementation of multispectral imaging model in computer graphics is analyzed, and a method to synthesize color from spectrum is provided. The multispectral imaging renderer and some problems of realization are simply introduced. Through four cases about color evaluation, object appearance reproduction with different materials, appearance effect of different illuminants and the algorithm of spectral reflectance reconstruction, and the applications of multispectral rendering method are presented.