A femtosecond pulsed laser with wavelength of 800 nm is used to process micro-pits on the surface of cemented carbide YG6. The morphology parameters and surface contact angles of these micro-pits are measured to obtain the optimal processing parameters. The effects of micro-pit shape, distribution density and single micro-pit area on the surface contact angle are analyzed. Based on the middle state theory of Wenzel and Cassie models, the influence mechanism of micro-pit shape on surface contact angle is analyzed. The results show that the micro-pit surface morphology is relatively good and there exists a linear relationship between the micro-pit depth and number of scanning when the average power is lower than 200 mW. The micro-pit surface contact angle decreases with the increase of micro-pit density and increases with the increase of single micro-pit area. The shapes of micro-pits in the order of excellence of surface wettability are as follows: regular triangle, regular square, regular hexagon and circle.