In the Report uring the 18th National Congress of the Communist Party of China in 2012, President Xi Jinping proposed that we should speed up the construction of an ecological civilization system and resolutely fight the battle against pollution, which is presented in the new round of ecological civilization construction work in Guangdong Province. According to the carrying capacity of regional resources and environment, we should incorporate environmental damage, ecological benefits and other indicators into the comprehensive evaluation system of development, and build a green ecological urban agglomeration in the Pearl River Delta. In this paper, through the construction of development intensity and bearing capacity index system, nine cities in the Pearl River Delta were selected as the research object, and the coupling coordination model was used to quantify the level of sustainable development, and the role of each subsystem was revealed through driving force analysis. The results show that: (1) The contrast of regional development intensity is obvious, and the characteristics of metropolitan area are becoming increasingly prominent. Among them, Shenzhen has the strongest degree of development and Zhaoqing was the weakest; (2) According to the driving factors, the carrying capacity of resources and environment in the region can be divided into natural pulled type and economic pulled type. The comprehensive carrying capacity can be consolidated through natural advantages and socio-economic input, respectively; (3) More than half of the urban eco-economic systems in the region are on the verge of being out of tune. Driven by economic factors, Guangzhou and Shenzhen are relatively more coordinated; (4) We should cope with three coordinated development states in the region, and formulate ecological restoration plans for local cities.