The nonlinear optical and optical limiting properties of the perfluorinated phthalocyaninatotitanium (IV) oxide (F16PcTiO) and its derivative F16PcTiO2PhCHO have been studied. Compared to F16PcTiO,the peak maxima of the Q-band of F16PcTiO2PhCHO is shifted to the red by Δλ=7 nm. Z-scan experimental results show that F16PcTiO exhibited much greater nonlinear absorption coefficient and lower saturable fluence for optical limiting when compared to F16PcTiO2PhCHO in solution. The latter displays much better optical limiting performance in chloroform than in toluene. In contrast to the highly soluble tetra (tert-butyl)-substituted titanium (IV) phthalocyanines,i.e.,tBu4PcTiO and tBu4PcTiO2PhCHO,the perfluorinated titanium (IV) phthalocyanines display stronger intermolecular interactions which are driven by enhanced Van der Waal′s attractive forces between phthalocyanine rings,and reducs the effective nonlinear absorption and the solubility in common organic solvents as well.