In order to solve the problem of high bit-error-rate of serial transceiver under strong channel attenuation,a low-power 112 Gibit/s SerDes transmitter is designed by using Duo-binary PAM4 coding technology.By adopting Duo-binary PAM4 coding technology,the problem of excessive attenuation of high-speed PAM4 (Pulse Amplitude Modulation-4) signal is solved.The system power consumption of the transmitter is reduced by using CMOS 1/4 speed architecture for 4∶1 MUX.The linearity of Duo-binary PAM4 transmitter is improved by using impedance calibration circuit.The transmitter is designed by CMOS 28 nm process and powered by 0.9 V voltage.The simulation results show that the transmitter can operate at 112 Gibit/s under the strong channel attenuation of 20.9 dB,with the power consumption of 1.9 pJ/bit and the linearity of 88.3%.