Study on Interaction Between Mitiglinide Calcium and Bovine Serum Albumin by Spectroscopy

Xiaotian Zhang; Lin Zhang; Weihua Zhu; Bo Yu

doi:10.3788/AOS201737.1130002

Journals >Acta Optica Sinica >Volume 37 >Issue 11 >Page 1130002 > Article

Acta Optica Sinica
Vol. 37, Issue 11, 1130002 (2017)

Study on Interaction Between Mitiglinide Calcium and Bovine Serum Albumin by Spectroscopy

Xiaotian Zhang¹, Lin Zhang^1、*, Weihua Zhu¹, and Bo Yu²

Author Affiliations

¹ College of Science, Hohai University, Nanjing, Jiangsu 211100, China

² College of Science, Nanjing University of Aeronautics and Astronautics, Nanjing, Jiangsu 210016, China

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DOI: 10.3788/AOS201737.1130002 Cite this Article Set citation alerts

Xiaotian Zhang, Lin Zhang, Weihua Zhu, Bo Yu. Study on Interaction Between Mitiglinide Calcium and Bovine Serum Albumin by Spectroscopy[J]. Acta Optica Sinica, 2017, 37(11): 1130002 Copy Citation Text

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Fig. 1. Quenching spectra of mitiglinide calcium to BSA

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Fig. 2. Stern-Volmer quenching curves of BSA after adding mitiglinide calcium

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Fig. 3. Fluorescence spectrum of BSA and ultraviolet visible absorption spectrum of mitiglinide calcium

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Fig. 4. Synchronous fluorescence spectra of mitiglinide calcium at different wavelength differences. (a) Δλ=15 nm; (b) Δλ=60 nm

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T /K	Stern-Volmer linear equation	R²	$\begin{matrix} {k_{q}}_{} \end{matrix}$ /(10⁵ L·mol^-1)
297	F₀/F=0.9544+8.78×10⁵c_q	0.97538	8.78
308	F₀/F=0.94165+1.304×10⁶c_q	0.99399	13.04

Table 1. Fitting equation, fitting degree R2 and quenching rate constant kq

Xiaotian Zhang, Lin Zhang, Weihua Zhu, Bo Yu. Study on Interaction Between Mitiglinide Calcium and Bovine Serum Albumin by Spectroscopy[J]. Acta Optica Sinica, 2017, 37(11): 1130002

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