Traditional match filter receiver suffers from multiple access interference and near-far effect in CDMA systems. Previous multi-user detection schemes proposed to mitigate the near-far problem and the multiple access interference are too complex to be implemented, as the cancellation schemes are all needed to reconstruct interfering users' signals. In this paper, an interference cancellation detector is proposed, which don't need to reconstruct each user's signal and cancel interference on symbol-level. It can effectively eliminate the amount of operation, improve the signal-to-noise ratio and accelerate processing as well. Numerical results are provided to show that this scheme offers significant performance compared with the match filter receiver.