• Acta Optica Sinica
  • Vol. 41, Issue 10, 1011001 (2021)
Jinhua Zhang1、2, Jizhou Zhang1、2、*, Jianan Li1、**, Jie Li3、***, Yiwen Chen1、2, Xin Wang1、2, Shushan Wang1、2, and Tingfa Xu1、2
Author Affiliations
  • 1Key Laboratory of Photoelectronic Imaging Technology and System, Ministry of Education of China, School of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, China
  • 2Chongqing Innovation Center, Beijing Institute of Technology, Chongqing 401120, China
  • 3Electronic Information Engineering College, Changchun University, Changchun, Jilin 130022, China
  • show less
    DOI: 10.3788/AOS202141.1011001 Cite this Article Set citation alerts
    Jinhua Zhang, Jizhou Zhang, Jianan Li, Jie Li, Yiwen Chen, Xin Wang, Shushan Wang, Tingfa Xu. Aberration Correction of Fourier Ptychographic Microscopy Based on Ptychographical Iterative Engine[J]. Acta Optica Sinica, 2021, 41(10): 1011001 Copy Citation Text show less

    Abstract

    With the aid of Fourier ptychographic microscopy, we can synthesize single-frame images with more details after spectrum expansion, thus reconstructing high-resolution images in a large field of view. However, the ubiquitous aberrations in imaging systems often lead to blurry images and reduce resolution of the reconstructed images. To solve the above problems, we proposed an innovative aberration correction method based on ptychographical iterative engine. Specifically, when updating the spectrum and pupil function, we adaptively selected the optimal ratio between their current and maximum values to improve the quality of iterative reconstruction. Then, we reconstructed the simulated images with mixed aberrations by taking peak signal-to-noise ratio (PSNR) and structural similarity (SSIM) as evaluation metrics. The simulation results showed that compared with the traditional embedded pupil recovery algorithm, our method sharply increased the PSNR and SSIM (14.9% and 1.4%, respectively). To further verify the effectiveness of our method on real images, we collected human blood cell samples for reconstruction. The reconstructed images were clear, which contributed to distinguishing the cell contours accurately.
    Jinhua Zhang, Jizhou Zhang, Jianan Li, Jie Li, Yiwen Chen, Xin Wang, Shushan Wang, Tingfa Xu. Aberration Correction of Fourier Ptychographic Microscopy Based on Ptychographical Iterative Engine[J]. Acta Optica Sinica, 2021, 41(10): 1011001
    Download Citation