Fig. 1. The results of the phantom experiment. (a) Slice and (g) 3D view of the true double fluorescence targets. (b) Slice and (h) 3D view of the reconstructed images obtained from the conventional method without data compression. (c)–(f) Slice and (i)–(l) 3D view of the reconstructed images obtained from the FDC strategy with 2, 3, 4, and 6 adjacent projections in each group. (m) Computational time consumed using different methods. (n) RMSEs and (o) normalized intensity profiles along the dotted line in (a) using different methods. All images are normalized by the maximal values of the results.

Fig. 2. Results of the in vivo mouse experiment. (a) Slice view of the in vivo mouse. (b) Slice and (f) 3D view of the reconstructed images obtained from the conventional method. (c)–(e) Slice and (g)–(i) 3D view of the reconstructed images obtained from the FDC with 2, 3, and 6 adjacent projections. (j) Computational time consumed using different methods. (k) RMSEs and (l) normalized intensity profiles along the dotted line in (a) using different methods. All images are normalized by the maximal values of the results.

Table 1. The Scales of Weight Matrix before and after Compression