Reduced graphene oxide-CuInS2 quantum dots (rGO/CuInS2-QDs) hybrids with different weight ratios of rGO and CuInS2-QDs are controllably synthesized by solvothermal method. Then graphene based hybrid polymer solar cells are fabricated by blending the rGO/CuInS2-QDs hybrid with poly(2-methoxy-5-(2-ethylhexyloxy)-1, 4-phenylene vinylene) (MEH-PPV) as photoactive layer, and the effects of the weight ratio (x) of rGO to CuInS2-QDs in rGO/CuInS2-QDs hybrid acceptor material and the weight ratio (w) of MEH-PPV donor material to rGO/CuInS2-QDs hybrid acceptor material in photoactive blend on device performance are studied. The results show that when the content of rGO/CuInS2?(x=0.25) hybrid acceptor material increases from 10% (w=9) to 17% (w=5), the electron collection efficiency (ηc) of the device increases from 0.61 to 0.78, which improves the photoelectric conversion efficiency of the device.