Research progress of laser conditioning technology and its applications in China is reviewed in this paper. The physical mechanisms, effects and key techniques of laser conditioning on 1ω dielectric coatings and potassium dihydrogen phosphate(KDP)and doped deuterium KDP (DKDP) crystals are studied. A laser conditioning platform for large-aperture optics is constructed to increase the laser damage resistance of critical optics used in high power laser systems. The laser conditioning for large-aperture 1ω dielectric coatings is realized on engineering working. The influences of laser pulse lengths on the laser damage performance of DKDP crystals are compared. It demonstrates that there no intrinsic damage during nanosecond laser irradiation until 14 J/cm2(5 ns) can be observed in sub-nanosecond conditioned DKDP crystals, so that the scheme proposed in the paper is verified to be feasibility. Finally, it points out that the sub-nanosecond laser conditioning will be the key technology to implement the anti-laser damage performance of the high laser harmonic generation crystals.