As an important link between human and natural systems, ecosystem services are closely related to human well-being and sustainable development. Land use/land cover change (LUCC) is one of the important drivers for ecosystem services change, and it has a significant impact on ecosystem services at the local, regional and global scales. Under the background of ecological civilization construction, it is very important to understand the spatial characteristics, differences and correlation at multi spatial scales. It is beneficial for studying the scale effect profoundly, coordinating the decision-making of multi-level management institutions and alleviating the constraints of scarce ecosystem services on socio-economic development. From the perspective of spatial scale, we summarized the concepts of spatial scale on this topic and introduced the analytical framework for considering spatial scale effect based on the recent theoretical and empirical developments. Then, we systematically analyzed the scale selection basis, features and correlation on the impact of LUCC on ecosystem services at different spatial scales, following the research thinking and process. Furthermore, we evaluated the research approach used to study the impact of LUCC on ecosystem services at both single scale and multi scales. This review put forward the key questions which should be considered in studies on the scale effect as follows: (1) building a research framework combining humanistic factors with natural factors; (2) explaining the scale effect of LUCC on ecosystem services; (3) exploring the effective analytical methods of the scale effect of LUCC on ecosystem services.