The absorption spectrum of natural abundan ce water vapor at 1.51 μm has been studied at room temperature by using a high-resolution tunable diode laser absorption spectrometer (TDLAS) combined with a long-path White absorption cell. A total of 57 absorption lines are investigated within the laser spectral range (6608～6624.3 cm-1). The line positions, line intensities and self-broadening coefficients of these lines are obtained by using a nonlinear least-squares fitting method, and then compared with the available values reported in the HITRAN 2016 database. Results show that the experimental data of present work is in good agreement with those from HITRAN 2016 database, which indicates that the spectral measurement system is suitable for study on the spectra of water vapor.