[1] W Chen, R Zheng, P. D Baade, S Zhang, H Zeng, F Bray, A Jemal, Q. Y Xue, H Jie. Cancer statistics in China, 2015. Cancer J. Clin, 66, 115-132(2016).
[2] R. L Siegel, K. D Miller, S. A Fedewa, D. J Ahnen, A Jemal. Colorectal cancer statistics. Cancer J. Clini, 67, 104-117(2017).
[3] M. B Schabath, M. L Cote. Cancer progress and priorities: Lung cancer. Cancer Epidemiol. Biomarkers Prev, 28, 1563-1579(2019).
[4] B. C Bade, C Cruz. Lung Cancer 2020: Epidemiology, etiology, and prevention — ScienceDirect. Clin. Chest Med, 41, 1-24(2020).
[5] M Phillips, J Herrera, S Krishnan, M Zain, J Greenberg, R. N Cataneo. Variation in volatile organic compounds in the breath of normal humans. J. Chromatograph. B. Biomed. Sci. Appl, 729, 75-88(1999).
[6] S Minami, S Ihara, K Komuta. Pretreatment lymphocyte to monocyte ratio as a prognostic marker for advanced pulmonary squamous cell carcinoma treated with chemotherapy. J. Clin. Med. Res, 10, 657-664(2018).
[7] J Xu. Cancer statistics. CA. Cancer J. Clin, 61, 10-29(2011).
[8] R. A Smith, A. V Eschenbach, R Wender, B Levin, T Byers, D Rothenberger, D Brooks, W Creasman, C Cohen, C Runowicz. American Cancer Society guidelines for the early detection of cancer. CA. Cancer J. Clin, 52, 8-22(2006).
[9] D. M Parkin, S. M Moss. Lung cancer screening. Cancer, 89, 2369-2376(2015).
[10] S. M Gordon, J. P Szidon, B. K Krotoszynski, R. D Gibbons, H. J O’neill. Volatile organic compounds in exhaled air from patients with lung cancer. Clin. Chem, 31, 1278-1282(1985).
[11] G. B Hanna, P. R Boshier, S. R Markar, A Romano. Accuracy and methodologic challenges of volatile organic compound-based exhaled breath tests for cancer diagnosis: A systematic review and meta-analysis. JAMA Oncol(2018).
[12] M Mlika, C Dziri, M. M Zorgati, M. B Khelil, F. E Mezni. Liquid biopsy as surrogate to tissue in lung cancer for molecular profiling: A meta-analysis. Curr. Resp. Med. Rev, 14, 48-60(2018).
[13] B. O Jansson, B Larsson. Analysis of organic compounds in human breath by gas chromatography-mass spectrometry. J. Lab Clin. Med, 74, 961-966(1969).
[14] B Arendacká, K Schwarz, S Tolc, G Wimmer, V Witkovsky. Variability issues in determining the concentration of isoprene in human breath by PTR-MS. J. Breath Res, 2, 037007(2008).
[15] M Wolff, Y Saalberg. VOC breath biomarkers in lung cancer. Clin. Chim. Acta Int. J. Clin. Chem. Appl. Mol. Biol, 459, 5-9(2016).
[16] A Ulanowska, T Kowalkowski, E Trawińska, B Buszewski. The application of statistical methods using VOCs to identify patients with lung cancer. J. Breath Res, 5, 46008-46008(2011).
[17] D Fuchs, H Jamnig, P Heininger, M Klieber, S Schroecksnadel, M Fiegl, M Hackl, H Denz, A Amann. Decline of exhaled isoprene in lung cancer patients correlates with immune activation. J. Breath Res, 6, 027101(2012).
[18] S Yuichi, K Yutaro, T Hiroaki, H Toyoaki, S Kazuo, I Toshio, A Takafumi, S Woosuck. Diagnosis by volatile organic compounds in exhaled breath from lung cancer patients using support vector machine algorithm. Sensors (Basel, Switzerland), 17, 287(2017).
[19] E. H Wahl, T. G Owano, C. H Kruger, P Zalicki, Y Ma, R. N Zare. Measurement of absolute CH3 concentration in a hot-filament reactor using cavity ring-down spectroscopy. Diam. Relat. Mater, 5, 373-377(1996).
[20] Q Li, J Li, X Wei, Y Li, M Sun. An exploratory study on online quantification of isoprene in human breath using cavity ringdown spectroscopy in the ultraviolet. Anal. Chim. Acta, 1131, 18-24(2020).
[21] D Perez-Guaita, V Kokoric, A Wilk, S Garrigues, B Mizaikoff. Towards the determination of isoprene in human breath using substrate-integrated hollow waveguide mid-infrared sensors. J. Breath Res, 8, 026003(2014).
[22] P Sahay, S Scherrer, C Wang. Measurements of the weak UV absorptions of isoprene and acetone at 261–275nm using cavity ringdown spectroscopy for evaluation of a potential portable ringdown breath analyzer. Sensors, 13, 8170-8187(2013).
[23] C Wang, A. B Surampudi. An acetone breath analyzer using s ringdown spectroscopy: An initial test with human subjects under various situations. Meas. Sci. Technol, 19, 105604 (10pp)(2008).
[24] A Bajtarevic, C Ager, M Pienz, M Klieber, K Schwarz, M Ligor, T Ligor, W Filipiak, H Denz, M Fiegl. Noninvasive detection of lung cancer by analysis of exhaled breath. BMC Cancer, 9, 1-16(2009).
[25] H. P Chan, C Lewis, P. S Thomas. Exhaled breath analysis: Novel approach for early detection of lung cancer. Lung Cancer, 63, 164-168(2009).
[26] S. W Harshman, B. A Geier, A Qualley, L. A Drummond, L Flory, M Fan, R Pitsch, C. C Grigsby, J. B Phillips, J Martin. Exhaled isoprene for monitoring recovery from acute hypoxic stress. J. Breath Res, 11, 047111(2017).
[27] S Mendis, P. A Sobotka, D. E Euler. Pentane and isoprene in expired air from humans: Gas-chromatographic analysis of single breath. Clin. Chem, 40, 1485(1994).
[28] I Kushch, B Arendacká, S Tolc, P Mochalski, W Filipiak, K Schwarz, L Schwentner, A Schmid, A Dzien, M Lechleitner. Breath isoprene–aspects of normal physiology related to age, gender and cholesterol profile as determined in a proton transfer reaction mass spectrometry study. Clin. Chem. Lab. Med, 46, 1011(2008).
[29] P Sukul, A Richter, J. K Schubert, W Miekisch. Deficiency and absence of endogenous isoprene in adults, disqualified its putative origin. Heliyon, 7, e05922(2021).
