Fig. 1. Flow chart of algorithm

Fig. 2. OCT B-scan images of human retina. (a) Normal retina image; (b) DME retina image; (c) Drusen retina image

Fig. 3. Speckle denoising of normal retina image. (a0)--(a4) Original OCT image with noise and images after speckle denoising by ACD, Curvelet, TV, and proposed method; (b0)--(b4) histograms corresponding to images in Figs. 3 (a0)--(a4); (c10)--(c44) enlarged ROIs V1--V4 corresponding to images in Figs. 3(a0)--(a4)

Fig. 4. Speckle denoising of DME retina image. (a0)--(a4) Original OCT image with noise and images after speckle denoising by ACD, Curvelet, TV, and proposed method; (b0)--(b4) histograms corresponding to images in Figs. 4 (a0)--(a4); (c10)--(c44) enlarged ROIs V1--V4 corresponding to images in Figs. 4(a0)--(a4)

Fig. 5. Speckle denoising of Drusen retina image. (a0)--(a4) Original OCT image and images after speckle denoising by ACD, Curvelet, TV, and proposed method; (b0)--(b4) histograms corresponding to images in Figs. 5(a0)--(a4); (c10)--(c44) enlarged ROIs V1--V4 corresponding to images in Figs. 5(a0)--(a4)

Table 1. Metrics of normal retina image experiment

Table 2. Metrics of DME retina image experiment

Table 3. Metrics of Drusen retina image experiment