Aiming at the problems of complex background and strong environment adaptability of fuze system, a short-range detection method based on laser and millimeter wave fusion for the application background of sea target orientation recognition and anti-jamming of new generation anti-ship missile was proposed in this paper. Firstly, the shortcomings of single-mode detection system were introduced from the applicaion status of laser and millimeter wave in fuze. In view of this deficiency, a compound detection scheme based on the dual-mode fusion was proposed, and the detection system structure, accurate time identification algorithm of pulsed laser in dynamic scene and fusion target detection method were studied. In this method, the consistency and stability of laser detection performance in complex scenes could be achieved. And by introducing the distance information obtained from laser detection system into millimeter wave target detection algorithm simultaneously, the efficiency and reliability of the algorithm were effectively improved. Through theoretical simulation analysis, the results show that the method in this paper can make up for the shortcomings of single detection system in anti-jamming, and effectively improve the efficiency and reliability of target detection, which can provide reference for the subsequent anti-jamming system design of proximity fuze.