Chengxiong WEI, Xin JIN, Peinan YIN, Chengwei WU, Wei ZHANG. Carbon Spheres for Photothermal Therapy of Tumor Cells: Rapid Preparation and High Photothermal Effect [J]. Journal of Inorganic Materials, 2021, 36(11): 1208

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- Journal of Inorganic Materials
- Vol. 36, Issue 11, 1208 (2021)

1. Formation process of the carbon spheres

2. Effects of molar ratios of pyrogallic acid to formaldehyde at (a) 2:1, (b) 1:1, (c) 1:2, and (d) 1:4 on morphologies of phenolic resin spheres

3. Effects of molar ratios of pyrogallol to formaldehyde at (a) 2 : 1, (b) 1 : 1, (c) 1 : 2, and (d) 1 : 4 on particle sizes of phenolic resin spheres

4. TEM morphologies of phenolic resin spheres (a) before and (b) after calcination, their (c) particle size analysis curves of dynamic light scattering and (d) thermogravimetric analysis curve of carbon spheres after calcination in N2 atmosphere

5. (a) FT-IR and (b) Raman spectra of phenolic resin spheres before and after calcination, (c) Zeta potential of carbon spheres in different dispersion medium and (d) absorbance percent of carbon spheres in different dispersion medium at 808 nm

6. Evaluation of photothermal effect of carbon spheres

7. Measurement of the photothermal conversion efficiency of carbon spheres

8. Viability of HaCaT cells co-cultured with different concentrations of carbon spheres for 24 and 48 h

9. Photothermal killing effect of carbon spheres on tumor cells with different laser irradiation time

10. Live/dead fluorescence images of tumor cells co-culcured with carbon spheres by different laser irradiation time (Green: live cells; Red: dead cells; Scale bar=200 μm)

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