Evaluation and testing system of CCD video processor for space application is proposed, and used in the aerospace reliability screening of industrial grade video processor. By using Field Programmable Gate Array (FPGA) as control processing core, these functions are designed and implemented including multi-channel analog CCD signal generation，the video processor work mode control, communications, data acquisition and etc., The system functional composition and working principle were introduced in detail. Actual evaluation and testing system was completed with integrating the forty CCD video processors in a single board. The system has been successfully applied in the dynamic build-in screening test of industrial grade video processor XRD98L63, and the system is stable and reliable. The test conditions was being maintained at 85℃ and 192 hours power on operation, and the effective test was finished about the function and performance of the video processor used in the same batch. Test result is zero on the nonconforming product rate, satisfying the qualification that single batch screening nonconforming rate is less than 5%. Reliability screening of industrial grade components for the space load applications is implemented.