In order to solve the error problem caused by misalignment of the lens optical axis and the target surface for two-dimensional digital speckle inclined axis measurement at a close range. A simple and effective lens distortion correction formula based on optical principle under different angles is worked out to modify the testing strain and at last the data correction effectiveness of calibraton strain formula is verified by standard specimen under compressive and tensile tests. The results show that the proposed method can eliminate the effect of misalignment distortion whose error is not exceed 9.24% so that the efficiency and accuracy of two-dimensional digital speckle correlation technology are improved.