• Journal of Innovative Optical Health Sciences
  • Vol. 9, Issue 4, 1642004 (2016)
Alla B. Bucharskaya1、*, Galina N. Maslyakova1, Svetlana S. Pakhomy1, Olga V. Zlobina1, Irina O. Bugaeva1, Nikita A. Navolokin1, Boris N. Khlebtsov2, Vladimir A. Bogatyrev2, Nikolai G. Khlebtsov2、3, and Valery V. Tuchin3、4、5
Author Affiliations
  • 1Saratov State Medical University n.a.V.I. Razumovsky 410012 Saratov, Russia
  • 2Institute of Biochemistry and Physiology of Plants and Microorganisms RAS 410049 Saratov, Russia
  • 3Research-Educational Institute of Optics and Biophotonics Saratov National Research State University 410012 Saratov, Russia
  • 4Institute of Precision Mechanics and Control RAS 410028 Saratov, Russia
  • 5Interdisciplinary Laboratory of Biophotonics Tomsk National Research State University, 634050 Tomsk, Russia
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    DOI: 10.1142/s1793545816420049 Cite this Article
    Alla B. Bucharskaya, Galina N. Maslyakova, Svetlana S. Pakhomy, Olga V. Zlobina, Irina O. Bugaeva, Nikita A. Navolokin, Boris N. Khlebtsov, Vladimir A. Bogatyrev, Nikolai G. Khlebtsov, Valery V. Tuchin. The morphological changes in the internal organs of laboratory animals after prolonged oral administration of gold nanoparticles[J]. Journal of Innovative Optical Health Sciences, 2016, 9(4): 1642004 Copy Citation Text show less
    References

    [1] V. Torchilin, Handbook of Nanobiomedical Research. Fundamentals, Applications and Recent Developments (In 4 Volumes), World Scientific, Singapore (2014).

    [2] M. Valcarcel, A. I. López-Lorente, Gold Nanoparticles in Analytical Chemistry, Elsevier, Amsterdam (2014).

    [3] E. Boisselier, D. Astruc, "Gold nanoparticles in nanomedicine: Preparations, imaging, diagnostics, therapies and toxicity," Chem. Rev. 38, 1759–1782 (2009).

    [4] L. A. Dykman, N. G. Khlebtsov, "Gold nanoparticles in biomedical applications: Recent advances and perspectives," Chem. Soc. Rev. 41, 2256– 2282 (2012).

    [5] E. C. Dreaden, A. M. Alkilany, X. Huang, C. J. Murphy, M. A. El-Sayed, "The golden age: Gold nanoparticles for biomedicine," Chem. Soc. Rev. 41, 2740–2779 (2012).

    [6] N. G. Khlebtsov, L. A. Dykman, "Biodistribution and toxicity of engineered gold nanoparticles: A review of in vitro and in vivo studies," Chem. Soc. Rev. 40, 1647–1671 (2011).

    [7] M. I. Stockman, "Nanoplasmonics: Past, present, and glimpse into future," Opt. Express 19, 22029– 22106 (2011).

    [8] N. G. Khlebtsov, L. A. Dykman, "Optical properties and biomedical applications of plasmonic nanoparticles," J. Quant. Spectr. Radiat. Transfer 111, 1–35 (2010).

    [9] M. A. Dobrovolskaia, S. E. McNeil, "Immunological properties of engineered nanomaterials," Nat. Nanotechnol. 2, 469–478 (2007).

    [10] P. C. Chen, S. C. Mwakwari, A. K. Oyelere, "Gold nanoparticles: From nanomedicine to nanosensing," Nanotechnol. Sci. Appl. 1, 45–66 (2008).

    [11] G. E. Abraham, "Clinical applications of gold and silver nanocolloids," Original Internist 15, 132–158 (2008).

    [12] H.-J. Yen, S.-H. Hsu, Ch.-L. Tsai, "Cytotoxicity and immunological response of gold and silver nanoparticles of different sizes," Small 5, 1553–1561 (2009).

    [13] P. R. Gil, G. Oberd€orster, A. Elder, V. Puntes, W. J. Parak, "Correlating physico-chemical with toxicological properties of nanoparticles: The present and the future," ACS Nano 4, 5527–5531 (2010).

    [14] A. M. Alkilany, C. J. Murphy, "Toxicity and cellular uptake of gold nanoparticles: What we have learned so far ," Nanopart. Res. 12, 2313–2333 (2010).

    [15] I. M. Paino, V. S. Marangoni, R. de Cassia Silva de Oliveira, L. M. G. Antunes, V. Zucolotto, "Cytoand genotoxicity of gold nanoparticles in human hepatocellular carcinoma and peripheral blood mononuclear cells," Toxicol. Lett. 215, 1191–1125 (2012).

    [16] M. Schulz, L. Ma-Hock, S. Brill, V. Strauss, S. Treumann, S. Gr€oters, B. van Ravenzwaay, R. Landsiedel, "Investigation on the genotoxicity of different sizes of gold nanoparticles administered to the lungs of rats," Mutat. Res. 745, 51–57 (2012).

    [17] S. Di Bucchianico, M. R. Fabrizi, S. Cirillo, C. Uboldi, D. Gilliland, E. Valsami-Jones, L. Migliore, "Aneuploidogenic effects and DNA oxidation induced in vitro by differently sized gold nanoparticles," Int. J. Nanomed. 9, 2191–2204 (2014).

    [18] S. Fraga, H. Faria, M. E. Soares, J. A. Duarte, L. Soares, E. Pereira, C. Costa-Pereira, J. P. Teixeira, M. de Lourdes Bastos, H. Carmo, "Influence of the surface coating on the cytotoxicity, genotoxicity and uptake of gold nanoparticles in human HepG2 cells," J. Appl. Toxicol. 10, 1111–1119 (2013).

    [19] H. Yang, C. Sun, Z. Fan, X. Tian, L. Yan, L. Du, Y. Liu, C. Chen, X.-J. Liang, G. J. Anderson, J. A. Keelan, Y. Zhao, G. Nie, "Effects of gestational age and surface modification on materno-fetal transfer of nanoparticles in murine pregnancy," Sci. Rep. 2, 847 (2012).

    [20] X. Tian, M. Zhu, L. Du, J. Wang, Z. Fan, J. Liu, Y. Zhao, G. Nie, "Intrauterine inflammation increases materno-fetal transfer of gold nanoparticles in a sizedependent manner in murine pregnancy," Small 9, 2432–2439 (2013).

    [21] N. A. Tsyganova, R. M. Khairullin, G. S. Terentyuk, B. N. Khlebtsov, V. A. Bogatyrev, L. A. Dykman, S. N. Erykov, N. G. Khlebtsov, "Penetration of pegylated gold nanoparticles through rat placental barrier," Bull. Exp. Biol. Med. 157, 383–389 (2014).

    [22] L. A. Dykman, N. G. Khlebtsov, "Uptake of engineered gold nanoparticles into mammalian cells," Chem. Rev. 114, 1258–1288 (2014).

    [23] J. F. Hillyer, R. M. Albrecht, "Gastrointestinal persorption and tissue distribution of differently sized colloidal gold nanoparticles," J. Pharm. Sci. 90, 1927–1936 (2001).

    [24] T. Jung, W. Kamm, A. Breitenbach, E. Kaiserling, J. X. Xiao, T. Kissel, "Biodegradable nanoparticles for oral delivery of peptides: Is there a role for polymers to affect mucosal uptake ," Eur. J. Pharm. Biopharm. 50, 147–160 (2000).

    [25] L. A. Dykman, V. A. Bogatyrev, S. Y. Shchegolev, N. G. Khlebtsov, Gold Nanoparticles: Synthesis, Properties, Biomedical Applications, Nauka, Moscow (2008) (in Russian).

    [26] G. Frens, "Controlled nucleation for the regulation of the particle size in monodisperse gold suspensions," Nat. Phys. Sci. 241, 20–22 (1973).

    [27] D. G. Duff, A. Baiker, P. P. Edwards, "A new hydrosol of gold clusters. 1. Formation and Particle Size Variatio," Langmuir 9, 2301–2309 (1993).

    [28] G. A. Merkulov, The Course of Patohistologic Technology, Medicine, Leningrad (1969) (in Russian).

    [29] International Guiding Principles for Biomedical Research Involving Animals, CIOMS&ICLAS, http://www.cioms.ch/index.php/12-newsflash/227- cioms-and-iclas-release-the-new-international-guiding- principles-for-biomedical-research-involvinganimals (2012).

    [30] I. M. Solopaeva, B. P. Solopaev, Stimulation of regeneration of the diseased liver and human chorionic gonadotropin, Nizhny Novgorod, Univ N. I. Lobachevsky (1991).

    [31] V. V. Sadovnikova, I. V. Sadovnikova, L. N. Ivanova, "Morphological changes in the liver of rats with drug-induced hepatitis and toxic stimulation of reparative processes," Morphology 120, 63–65 (2001).

    [32] E. I. Galanzha, M. S. Kokoska, E. V. Shashkov, J. W. Kim, V. V. Tuchin, V. P. Zharov, "In vivo fiberbased multicolor photoacoustic detection and photothermal purging of metastasis in sentinel lymph nodes targeted by nanoparticles," J. Biophoton. 2, 528–539 (2009).

    [33] E. Song, H. Seo, K. Choe, Y. Hwang, J. Ahn, S. Ahn, P. Kim, "Optical clearing based cellular-level 3D visualization of intact lymph node cortex," Biomed. Opt. Express 6, (2015). doi: 10.1364/ BOE.6.004154.

    [34] S. V. German, O. A. Inozemtseva, N. A. Navolokin, E. E. Pudovkina, V. V. Zuev, E. K. Volkova, A. B. Bucharskaya, S. N. Pleskova, G. N. Maslyakova, D. A. Gorin, "Synthesis of magnetite hydrosols and assessment of their impact on living systems at the cellular and tissue levels using MRI and morphological investigation," Nanotechnol. Russia 8, 573– 580 (2013).

    Alla B. Bucharskaya, Galina N. Maslyakova, Svetlana S. Pakhomy, Olga V. Zlobina, Irina O. Bugaeva, Nikita A. Navolokin, Boris N. Khlebtsov, Vladimir A. Bogatyrev, Nikolai G. Khlebtsov, Valery V. Tuchin. The morphological changes in the internal organs of laboratory animals after prolonged oral administration of gold nanoparticles[J]. Journal of Innovative Optical Health Sciences, 2016, 9(4): 1642004
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