• Journal of Inorganic Materials
  • Vol. 37, Issue 11, 1192 (2022)
Wenjun ZHANG1, Xueying ZHAO1, Jiangwei LÜ1、*, and Youpeng QU2
Author Affiliations
  • 11. School of Pharmacy, Harbin University of Commerce, Harbin 150076, China
  • 22. School of Life Science and Technology, Harbin Institute of Technology, Harbin 150080, China
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    DOI: 10.15541/jim20220435 Cite this Article
    Wenjun ZHANG, Xueying ZHAO, Jiangwei LÜ, Youpeng QU. Progresses on Hollow Periodic Mesoporous Organosilicas: Preparation and Application in Tumor Therapy[J]. Journal of Inorganic Materials, 2022, 37(11): 1192 Copy Citation Text show less
    Preparation of HPMOs and their application in tumor therapy
    1. Preparation of HPMOs and their application in tumor therapy
    Structures of HPMOs, yolk-shell HPMOs and multishelled HPMOs
    2. Structures of HPMOs, yolk-shell HPMOs and multishelled HPMOs
    Synthetic processes for yolk-shell structured HPMOs and HPMOs
    3. Synthetic processes for yolk-shell structured HPMOs and HPMOs
    TEM images of (a) yolk-shell HPMOs and (b) HPMOs obtained by HF etching [34]
    4. TEM images of (a) yolk-shell HPMOs and (b) HPMOs obtained by HF etching [34]
    Preparation process of HPMOs by interface recombination-transformation method [35]
    5. Preparation process of HPMOs by interface recombination-transformation method [35]
    Drug delivery process of HPMOs [34]
    6. Drug delivery process of HPMOs [34]
    DOX release process of photoresponsive drug delivery system[67]
    7. DOX release process of photoresponsive drug delivery system[67]
    Scheme of the polymerization within HMPDINs for photocontrolled drug release [71]
    8. Scheme of the polymerization within HMPDINs for photocontrolled drug release [71]
    CO release process of reduction responsive drug delivery system[72]
    9. CO release process of reduction responsive drug delivery system[72]
    Hard-core templating methodLiquid-interface assembly method Interfacial reassembly and transformation method
    Synthesis strategyDifference①Using solid particles as template②Etchant required①Using droplets or micelles as templates②No etchant required①No sacrificial template required②No etchant required
    SimilarityThe surfactant was extracted by HCl/EtOH solution
    Influence factor①Amount and type of etchant②Etching temperature③SNs size and organosilicon source concentrationStability of droplets or micellesHydrothermal time and temperature
    AdvantagesEasy to control cavity diameter①No sacrificial template required②No etchant required③Simple operation①No sacrificial template required②No etchant required
    Disadvantages①High costs②Cumbersome operation③Some of etchants are toxic①Stability of droplets or micelles should be consideredHigh temperature of hydrothermal process
    Table 1. Comparison of preparation methods of HPMOs
    Wenjun ZHANG, Xueying ZHAO, Jiangwei LÜ, Youpeng QU. Progresses on Hollow Periodic Mesoporous Organosilicas: Preparation and Application in Tumor Therapy[J]. Journal of Inorganic Materials, 2022, 37(11): 1192
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