The treatment of skin vascular disease with all-solid-state laser is a safe, effective and successful option. We review literatures on the laser technique for treatment of skin vascular disease. The absorption peak of oxyhemoglobin and the selective absorption principle of tissue are introduced. The main techniques for generating 418, 542 and 577 nm laser are discussed. The yellow 577 nm medical laser techniques including frequency doubling, sum frequency mixing, stimulated Raman scattering (SRS), optical parametric oscillator (OPO)and optically pumped semiconductor (OPS) are emphasized. The advantages and the development trend of different ways are pointed out. In the discussion of sum frequency mixing, the new scheme to produce 578 nm laser by employing thin disc and end-pumping configuration is demonstrated.