• Journal of Radiation Research and Radiation Processing
  • Vol. 40, Issue 6, 060301 (2022)
Huichao LI1, Mingjuan ZHAO2, and Long TIAN1、*
Author Affiliations
  • 1The First Affiliated Hospital of Hebei Northern University, Zhangjiakou 075000, China
  • 2Hebei General Hospital, Shijiazhuang 050000, China
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    DOI: 10.11889/j.1000-3436.2022-0040 Cite this Article
    Huichao LI, Mingjuan ZHAO, Long TIAN. Study on the therapeutic mechanism and effect of metformin combined with single high-dose radiotherapy in mice with non-small cell lung cancer[J]. Journal of Radiation Research and Radiation Processing, 2022, 40(6): 060301 Copy Citation Text show less
    References

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    [2] Luo YANG, Yarong HAO. Research progress on pharmacological effects of metformin. Medical Recapitulate, 25, 1816-1821(2019).

    [3] Gaoxiang WANG, Meiqing XU, Mingran XIE. Research advance in anti-lung cancer mechanism of metformin. Chinese Journal of Lung Cancer, 23, 282-285(2020).

    [4] Chunqing MU, Lei ZHOU, Nan ZHAO et al. Effect of metformin on proliferation of lung cancer A549 cells through PI3K/AKT/GSK3β signaling pathway. Journal of Jilin University (Medicine Edition), 47, 637-643(2021).

    [5] C W Song, Y J Lee, R J Griffin et al. Indirect tumor cell death after high-dose hypofractionated irradiation: implications for stereotactic body radiation therapy and stereotactic radiation surgery. International Journal of Radiation Oncology*Biology*Physics, 93, 166-172(2015).

    [6] Q Matthews, M Isabelle, S J Harder et al. Radiation-induced glycogen accumulation detected by single cell Raman spectroscopy is associated with radioresistance that can Be reversed by metformin. PLoS One, 10, e0135356(2015).

    [7] S L Brown, A Kolozsvary, D M Isrow et al. A novel mechanism of high dose radiation sensitization by metformin. Frontiers in Oncology, 9, 247(2019).

    [8] Wanyi GUO, Bei YUAN, Nixue ZHANG et al. Effect of reactive oxygen species (ROS) on bone destruction in rheumatoid arthritis. Chinese Journal of Immunology, 37, 2182-2186(2021).

    [9] Riyun YANG, Jingying PAN, Yi LI et al. Protective effect of menaquinone-4 on oligodendrocytes under hypoxia. Chinese Journal of Anatomy, 43, 388-392(2020).

    [10] M Elgendy, M Cirò, A Hosseini et al. Combination of hypoglycemia and metformin impairs tumor metabolic plasticity and growth by modulating the PP2A-GSK3β-MCL-1 axis. Cancer Cell, 35, 798-815(2019).

    [11] Qian GUO, Qianmei REN, Xiguang MAO et al. Effect of metformin on proliferation and chemosensitivity of cervical cancer stem cells. Chinese Journal of Gerontology, 41, 5351-5356(2021).

    [12] Lu QIAO, Yitao JIA. Research progress of metformin in the treatment of colorectal cancer. Journal of Digestive Oncology (Electronic Version), 13, 25-28(2021).

    [13] Yucheng SUN, Xiaowei LIU, Guangzhe PIAN. Effect of metformin on radiosensitivity of rectal cancer cells. Chinese Journal of Oncology Prevention and Treatment, 11, 37-42(2019).

    [14] R J O Dowling, S Lam, C Bassi et al. Metformin pharmacokinetics in mouse tumors: implications for human therapy. Cell Metabolism, 23, 567-568(2016).

    [15] Meiye LI, Wenchao XU, Wei QU et al. The effects of metformin on survival of diabetic patients complicated with lung cancer. Labeled Immunoassays and Clinical Medicine, 27, 1147-1150(2020).

    Huichao LI, Mingjuan ZHAO, Long TIAN. Study on the therapeutic mechanism and effect of metformin combined with single high-dose radiotherapy in mice with non-small cell lung cancer[J]. Journal of Radiation Research and Radiation Processing, 2022, 40(6): 060301
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